Introduction to genetic linkage analysis

Research output: Contribution to journalReview article

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Abstract

Advances in molecular methodology have resulted in the successful genetic mapping and isolation of the genes responsible for numerous simple Mendelian disorders such as cystic fibrosis, neurofibromatosis, and Huntington disease. Recently, researchers have begun to successfully study diseases with more complex inheritance, such as breast cancer. This paper will provide a basic introduction to the strategies and methods commonly used in the localization of genes resulting in disease.

Original languageEnglish (US)
Pages (from-to)548-552
Number of pages5
JournalCancer Investigation
Volume15
Issue number6
DOIs
StatePublished - Jan 1 1997

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ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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