Is continuous veno-venous hemofiltration for acetaminophen-induced acute liver and renal failure worthwhile?

R. Agarwal, M. O. Farber

Research output: Contribution to journalArticle

15 Scopus citations


We describe a patient with acute liver and renal failure secondary to acetaminophen and chronic alcohol abuse who was treated aggressively with oral acetylcysteine, continuous renal replacement therapy, glucose and branched-chain amino acid intravenous feeding and ventilatory support. The patient had a predicted mortality of >95% without liver transplantation however, with intensive ventilatory, renal, and nutritional support he made a complete recovery. We discuss the benefits of aggressive supportive therapy and suggest that continuous renal replacement therapy may allow gentle fluid removal, excellent control of cerebral edema and intravenous feeding that may favorably influence prognosis.

Original languageEnglish (US)
Pages (from-to)167-170
Number of pages4
JournalClinical Nephrology
Issue number2
StatePublished - Jan 1 2002



  • Acetaminophen
  • Acute renal failure
  • Continuous renal replacement therapies
  • Intravenous nutrition

ASJC Scopus subject areas

  • Nephrology

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