Is continuous veno-venous hemofiltration for acetaminophen-induced acute liver and renal failure worthwhile?

R. Agarwal, M. O. Farber

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

We describe a patient with acute liver and renal failure secondary to acetaminophen and chronic alcohol abuse who was treated aggressively with oral acetylcysteine, continuous renal replacement therapy, glucose and branched-chain amino acid intravenous feeding and ventilatory support. The patient had a predicted mortality of >95% without liver transplantation however, with intensive ventilatory, renal, and nutritional support he made a complete recovery. We discuss the benefits of aggressive supportive therapy and suggest that continuous renal replacement therapy may allow gentle fluid removal, excellent control of cerebral edema and intravenous feeding that may favorably influence prognosis.

Original languageEnglish (US)
Pages (from-to)167-170
Number of pages4
JournalClinical Nephrology
Volume57
Issue number2
DOIs
StatePublished - Jan 1 2002

Fingerprint

Hemofiltration
Renal Replacement Therapy
Acute Liver Failure
Parenteral Nutrition
Acetaminophen
Acute Kidney Injury
Branched Chain Amino Acids
Nutritional Support
Brain Edema
Acetylcysteine
Liver Transplantation
Alcoholism
Kidney
Glucose
Mortality
Therapeutics

Keywords

  • Acetaminophen
  • Acute renal failure
  • Continuous renal replacement therapies
  • Intravenous nutrition

ASJC Scopus subject areas

  • Nephrology

Cite this

Is continuous veno-venous hemofiltration for acetaminophen-induced acute liver and renal failure worthwhile? / Agarwal, R.; Farber, M. O.

In: Clinical Nephrology, Vol. 57, No. 2, 01.01.2002, p. 167-170.

Research output: Contribution to journalArticle

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