Is Fasting Necessary for Individuals With Nonalcoholic Fatty Liver Disease to Undergo Vibration-Controlled Transient Elastography?

Raj Vuppalanchi, Regina Weber, Sarah Russell, Samer Gawrieh, Niharika Samala, James E. Slaven, Lauren Harden, Naga Chalasani

Research output: Contribution to journalArticle

Abstract

OBJECTIVES: To investigate the effect of meal intake on liver stiffness measurement (LSM) and controlled attenuation parameter (CAP) in patients with biopsy-proven nonalcoholic fatty liver disease undergoing vibration-controlled transient elastography. METHODS: LSM and CAP were assessed at baseline and serially for 6 hours after meal intake in 24 patients. RESULTS: A significant increase in LSM was seen up to the 2-hour time point (26 ± 25%, P = 0.02). The CAP scores changed minimally with a maximal change of 3% (P > 0.1). CONCLUSIONS: Three hours of fasting is necessary before evaluation with vibration-controlled transient elastography.

Original languageEnglish (US)
Pages (from-to)995-997
Number of pages3
JournalThe American journal of gastroenterology
Volume114
Issue number6
DOIs
StatePublished - Jun 1 2019

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Elasticity Imaging Techniques
Vibration
Fasting
Meals
Liver
Biopsy
Non-alcoholic Fatty Liver Disease

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

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Is Fasting Necessary for Individuals With Nonalcoholic Fatty Liver Disease to Undergo Vibration-Controlled Transient Elastography? / Vuppalanchi, Raj; Weber, Regina; Russell, Sarah; Gawrieh, Samer; Samala, Niharika; Slaven, James E.; Harden, Lauren; Chalasani, Naga.

In: The American journal of gastroenterology, Vol. 114, No. 6, 01.06.2019, p. 995-997.

Research output: Contribution to journalArticle

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abstract = "OBJECTIVES: To investigate the effect of meal intake on liver stiffness measurement (LSM) and controlled attenuation parameter (CAP) in patients with biopsy-proven nonalcoholic fatty liver disease undergoing vibration-controlled transient elastography. METHODS: LSM and CAP were assessed at baseline and serially for 6 hours after meal intake in 24 patients. RESULTS: A significant increase in LSM was seen up to the 2-hour time point (26 ± 25{\%}, P = 0.02). The CAP scores changed minimally with a maximal change of 3{\%} (P > 0.1). CONCLUSIONS: Three hours of fasting is necessary before evaluation with vibration-controlled transient elastography.",
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AU - Weber, Regina

AU - Russell, Sarah

AU - Gawrieh, Samer

AU - Samala, Niharika

AU - Slaven, James E.

AU - Harden, Lauren

AU - Chalasani, Naga

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AB - OBJECTIVES: To investigate the effect of meal intake on liver stiffness measurement (LSM) and controlled attenuation parameter (CAP) in patients with biopsy-proven nonalcoholic fatty liver disease undergoing vibration-controlled transient elastography. METHODS: LSM and CAP were assessed at baseline and serially for 6 hours after meal intake in 24 patients. RESULTS: A significant increase in LSM was seen up to the 2-hour time point (26 ± 25%, P = 0.02). The CAP scores changed minimally with a maximal change of 3% (P > 0.1). CONCLUSIONS: Three hours of fasting is necessary before evaluation with vibration-controlled transient elastography.

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