Is Fasting Necessary for Individuals with Nonalcoholic Fatty Liver Disease to Undergo Vibration-Controlled Transient Elastography?

Raj Vuppalanchi, Regina Weber, Sarah Russell, Samer Gawrieh, Niharika Samala, James E. Slaven, Lauren Harden, Naga Chalasani

Research output: Contribution to journalArticle


To investigate the effect of meal intake on liver stiffness measurement (LSM) and controlled attenuation parameter (CAP) in patients with biopsy-proven nonalcoholic fatty liver disease undergoing vibration-controlled transient elastography.METHODS:LSM and CAP were assessed at baseline and serially for 6 hours after meal intake in 24 patients.RESULTS:A significant increase in LSM was seen up to the 2-hour time point (26 ± 25%, P = 0.02). The CAP scores changed minimally with a maximal change of 3% (P > 0.1).CONCLUSIONS:Three hours of fasting is necessary before evaluation with vibration-controlled transient elastography.

Original languageEnglish (US)
Pages (from-to)995-997
Number of pages3
JournalAmerican Journal of Gastroenterology
Issue number6
StatePublished - Jun 1 2019


ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

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