Is personalized medicine achievable in obstetrics?

Sara Quinney, Avinash S. Patil, David A. Flockhart

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Personalized medicine seeks to identify the right dose of the right drug for the right patient at the right time. Typically, individualization of therapy is based on the pharmacogenomic makeup of the individual and environmental factors that alter drug disposition and response. In addition to these factors, during pregnancy, a woman's body undergoes many changes that can impact the therapeutic efficacy of medications. Yet, there is minimal research regarding personalized medicine in obstetrics. Adoption of pharmacogenetic testing into the obstetrical care is dependent on evidence of analytical validity, clinical validity, and clinical utility. Here, we briefly present information regarding the potential utility of personalized medicine for treating the obstetric patient for pain with narcotics, hypertension, and preterm labor, and discuss the impediments of bringing personalized medicine to the obstetrical clinic.

Original languageEnglish
Pages (from-to)534-540
Number of pages7
JournalSeminars in Perinatology
Volume38
Issue number8
DOIs
StatePublished - Dec 1 2014

Fingerprint

Precision Medicine
Obstetrics
Labor Pain
Premature Obstetric Labor
Pharmacogenetics
Narcotics
Patient Rights
Pharmaceutical Preparations
Hypertension
Pregnancy
Therapeutics
Research

Keywords

  • Medications
  • Obstetrics
  • Personalized medicine
  • Pharmacogenetics

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

Cite this

Is personalized medicine achievable in obstetrics? / Quinney, Sara; Patil, Avinash S.; Flockhart, David A.

In: Seminars in Perinatology, Vol. 38, No. 8, 01.12.2014, p. 534-540.

Research output: Contribution to journalArticle

Quinney, Sara ; Patil, Avinash S. ; Flockhart, David A. / Is personalized medicine achievable in obstetrics?. In: Seminars in Perinatology. 2014 ; Vol. 38, No. 8. pp. 534-540.
@article{4f50a49159854927b6d9035a558a6538,
title = "Is personalized medicine achievable in obstetrics?",
abstract = "Personalized medicine seeks to identify the right dose of the right drug for the right patient at the right time. Typically, individualization of therapy is based on the pharmacogenomic makeup of the individual and environmental factors that alter drug disposition and response. In addition to these factors, during pregnancy, a woman's body undergoes many changes that can impact the therapeutic efficacy of medications. Yet, there is minimal research regarding personalized medicine in obstetrics. Adoption of pharmacogenetic testing into the obstetrical care is dependent on evidence of analytical validity, clinical validity, and clinical utility. Here, we briefly present information regarding the potential utility of personalized medicine for treating the obstetric patient for pain with narcotics, hypertension, and preterm labor, and discuss the impediments of bringing personalized medicine to the obstetrical clinic.",
keywords = "Medications, Obstetrics, Personalized medicine, Pharmacogenetics",
author = "Sara Quinney and Patil, {Avinash S.} and Flockhart, {David A.}",
year = "2014",
month = "12",
day = "1",
doi = "10.1053/j.semperi.2014.08.017",
language = "English",
volume = "38",
pages = "534--540",
journal = "Seminars in Perinatology",
issn = "0146-0005",
publisher = "W.B. Saunders Ltd",
number = "8",

}

TY - JOUR

T1 - Is personalized medicine achievable in obstetrics?

AU - Quinney, Sara

AU - Patil, Avinash S.

AU - Flockhart, David A.

PY - 2014/12/1

Y1 - 2014/12/1

N2 - Personalized medicine seeks to identify the right dose of the right drug for the right patient at the right time. Typically, individualization of therapy is based on the pharmacogenomic makeup of the individual and environmental factors that alter drug disposition and response. In addition to these factors, during pregnancy, a woman's body undergoes many changes that can impact the therapeutic efficacy of medications. Yet, there is minimal research regarding personalized medicine in obstetrics. Adoption of pharmacogenetic testing into the obstetrical care is dependent on evidence of analytical validity, clinical validity, and clinical utility. Here, we briefly present information regarding the potential utility of personalized medicine for treating the obstetric patient for pain with narcotics, hypertension, and preterm labor, and discuss the impediments of bringing personalized medicine to the obstetrical clinic.

AB - Personalized medicine seeks to identify the right dose of the right drug for the right patient at the right time. Typically, individualization of therapy is based on the pharmacogenomic makeup of the individual and environmental factors that alter drug disposition and response. In addition to these factors, during pregnancy, a woman's body undergoes many changes that can impact the therapeutic efficacy of medications. Yet, there is minimal research regarding personalized medicine in obstetrics. Adoption of pharmacogenetic testing into the obstetrical care is dependent on evidence of analytical validity, clinical validity, and clinical utility. Here, we briefly present information regarding the potential utility of personalized medicine for treating the obstetric patient for pain with narcotics, hypertension, and preterm labor, and discuss the impediments of bringing personalized medicine to the obstetrical clinic.

KW - Medications

KW - Obstetrics

KW - Personalized medicine

KW - Pharmacogenetics

UR - http://www.scopus.com/inward/record.url?scp=84918570775&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84918570775&partnerID=8YFLogxK

U2 - 10.1053/j.semperi.2014.08.017

DO - 10.1053/j.semperi.2014.08.017

M3 - Article

VL - 38

SP - 534

EP - 540

JO - Seminars in Perinatology

JF - Seminars in Perinatology

SN - 0146-0005

IS - 8

ER -