Ischemic Spinal Cord Infarction in Children Without Vertebral Fracture

Jessica R. Nance, Meredith Golomb

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Spinal cord infarction in children is a rare condition that is becoming more widely recognized. There are few reports in the pediatric literature characterizing etiology, diagnosis, treatment, and prognosis. The risk factors for pediatric ischemic spinal cord infarction include obstruction of blood flow associated with cardiovascular compromise or malformation, iatrogenic or traumatic vascular injury, cerebellar herniation, thrombotic or embolic disease, infection, and vasculitis. In many children, the cause of spinal cord ischemia in the absence of vertebral fracture is unknown. Imaging diagnosis of spinal cord ischemia is often difficult, due to the small transverse area of the cord, cerebrospinal fluid artifact, and inadequate resolution of magnetic resonance imaging. Physical therapy is the most important treatment option. The prognosis is dependent on the level of spinal cord damage, early identification and reversal of ischemia, and follow-up with intensive physical therapy and medical support. In addition to summarizing the literature regarding spinal cord infarction in children without vertebral fracture, this review article adds two cases to the literature that highlight the difficulties and controversies in the management of this condition.

Original languageEnglish
Pages (from-to)209-216
Number of pages8
JournalPediatric Neurology
Volume36
Issue number4
DOIs
StatePublished - Apr 2007

Fingerprint

Infarction
Spinal Cord
Spinal Cord Ischemia
Pediatrics
Encephalocele
Vascular System Injuries
Therapeutics
Vasculitis
Artifacts
Cerebrospinal Fluid
Ischemia
Magnetic Resonance Imaging
Infection

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health
  • Developmental Neuroscience
  • Neurology

Cite this

Ischemic Spinal Cord Infarction in Children Without Vertebral Fracture. / Nance, Jessica R.; Golomb, Meredith.

In: Pediatric Neurology, Vol. 36, No. 4, 04.2007, p. 209-216.

Research output: Contribution to journalArticle

@article{32c8c9dfda824e2cb9d380b92982444a,
title = "Ischemic Spinal Cord Infarction in Children Without Vertebral Fracture",
abstract = "Spinal cord infarction in children is a rare condition that is becoming more widely recognized. There are few reports in the pediatric literature characterizing etiology, diagnosis, treatment, and prognosis. The risk factors for pediatric ischemic spinal cord infarction include obstruction of blood flow associated with cardiovascular compromise or malformation, iatrogenic or traumatic vascular injury, cerebellar herniation, thrombotic or embolic disease, infection, and vasculitis. In many children, the cause of spinal cord ischemia in the absence of vertebral fracture is unknown. Imaging diagnosis of spinal cord ischemia is often difficult, due to the small transverse area of the cord, cerebrospinal fluid artifact, and inadequate resolution of magnetic resonance imaging. Physical therapy is the most important treatment option. The prognosis is dependent on the level of spinal cord damage, early identification and reversal of ischemia, and follow-up with intensive physical therapy and medical support. In addition to summarizing the literature regarding spinal cord infarction in children without vertebral fracture, this review article adds two cases to the literature that highlight the difficulties and controversies in the management of this condition.",
author = "Nance, {Jessica R.} and Meredith Golomb",
year = "2007",
month = "4",
doi = "10.1016/j.pediatrneurol.2007.01.006",
language = "English",
volume = "36",
pages = "209--216",
journal = "Pediatric Neurology",
issn = "0887-8994",
publisher = "Elsevier Inc.",
number = "4",

}

TY - JOUR

T1 - Ischemic Spinal Cord Infarction in Children Without Vertebral Fracture

AU - Nance, Jessica R.

AU - Golomb, Meredith

PY - 2007/4

Y1 - 2007/4

N2 - Spinal cord infarction in children is a rare condition that is becoming more widely recognized. There are few reports in the pediatric literature characterizing etiology, diagnosis, treatment, and prognosis. The risk factors for pediatric ischemic spinal cord infarction include obstruction of blood flow associated with cardiovascular compromise or malformation, iatrogenic or traumatic vascular injury, cerebellar herniation, thrombotic or embolic disease, infection, and vasculitis. In many children, the cause of spinal cord ischemia in the absence of vertebral fracture is unknown. Imaging diagnosis of spinal cord ischemia is often difficult, due to the small transverse area of the cord, cerebrospinal fluid artifact, and inadequate resolution of magnetic resonance imaging. Physical therapy is the most important treatment option. The prognosis is dependent on the level of spinal cord damage, early identification and reversal of ischemia, and follow-up with intensive physical therapy and medical support. In addition to summarizing the literature regarding spinal cord infarction in children without vertebral fracture, this review article adds two cases to the literature that highlight the difficulties and controversies in the management of this condition.

AB - Spinal cord infarction in children is a rare condition that is becoming more widely recognized. There are few reports in the pediatric literature characterizing etiology, diagnosis, treatment, and prognosis. The risk factors for pediatric ischemic spinal cord infarction include obstruction of blood flow associated with cardiovascular compromise or malformation, iatrogenic or traumatic vascular injury, cerebellar herniation, thrombotic or embolic disease, infection, and vasculitis. In many children, the cause of spinal cord ischemia in the absence of vertebral fracture is unknown. Imaging diagnosis of spinal cord ischemia is often difficult, due to the small transverse area of the cord, cerebrospinal fluid artifact, and inadequate resolution of magnetic resonance imaging. Physical therapy is the most important treatment option. The prognosis is dependent on the level of spinal cord damage, early identification and reversal of ischemia, and follow-up with intensive physical therapy and medical support. In addition to summarizing the literature regarding spinal cord infarction in children without vertebral fracture, this review article adds two cases to the literature that highlight the difficulties and controversies in the management of this condition.

UR - http://www.scopus.com/inward/record.url?scp=34247108295&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34247108295&partnerID=8YFLogxK

U2 - 10.1016/j.pediatrneurol.2007.01.006

DO - 10.1016/j.pediatrneurol.2007.01.006

M3 - Article

VL - 36

SP - 209

EP - 216

JO - Pediatric Neurology

JF - Pediatric Neurology

SN - 0887-8994

IS - 4

ER -