Isolation and characterization of Streptomyces spp. from soil showing broad spectrum antibiotic activity

Sewook Park, Taeok Bae, Seung Bum Kim

Research output: Contribution to journalArticle

Abstract

Three actinobacterial strains exhibiting broad spectrum antibiotic activities were isolated from soil, and characterized. Through the comparative analysis of 16S rRNA genes, the three isolates could be assigned to the genus Streptomyces, as S. tanashiensis, S. nashivillensis, and S. rubiginosohelvolus were found to be the mostly related species, but the strains formed independent phylogenetic lineage. Each strain exhibited different antimicrobial profile against Gram-positive bacteria Bacillus subtilis and Staphylococcus aureus, Gram-negative bacteria Salmonella typhi, Enterobacter cloacae, Serratia marcescens, and Pseudomonas aeruginosa, and also fungi Candida tropicalis and Candida krusei. In addition to the antimicrobial profile, the strains also differed in API ZYM test results, which implies that the three strains might produce difference antimicrobial substances.

Original languageEnglish
Pages (from-to)270-274
Number of pages5
JournalKorean Journal of Microbiology
Volume48
Issue number4
DOIs
StatePublished - 2012

Fingerprint

Candida tropicalis
Enterobacter cloacae
Salmonella typhi
Serratia marcescens
Streptomyces
Gram-Positive Bacteria
Bacillus subtilis
Gram-Negative Bacteria
rRNA Genes
Candida
Pseudomonas aeruginosa
Staphylococcus aureus
Fungi
Soil
Anti-Bacterial Agents

Keywords

  • Antimicrobial activity
  • Streptomyces

ASJC Scopus subject areas

  • Microbiology

Cite this

Isolation and characterization of Streptomyces spp. from soil showing broad spectrum antibiotic activity. / Park, Sewook; Bae, Taeok; Kim, Seung Bum.

In: Korean Journal of Microbiology, Vol. 48, No. 4, 2012, p. 270-274.

Research output: Contribution to journalArticle

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