Issues in genetic testing for susceptibility to alcoholism: Lessons from Alzheimer's disease and Huntington's disease

Kimberly A. Quaid, Stephen H. Dinwiddie, P. Michael Conneally, John Nurnberger

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Evidence from family, twin, and adoption studies suggests a heritable basis for alcoholism. However, alcoholism is likely to be genetically heterogeneous, and any genetic connection is likely to be in the form of genes conferring an increased risk or susceptibility. In this study, we present the evidence for a genetic component for alcoholism, and examine the precedent for genetic testing and screening for genetic susceptibility using Huntington's disease and Alzheimer's disease as examples. Finally, we discuss the preparations that need to be made before taking any findings about the genetics of alcoholism from the research laboratory into the clinic.

Original languageEnglish
Pages (from-to)1430-1437
Number of pages8
JournalAlcoholism: Clinical and Experimental Research
Volume20
Issue number8
StatePublished - 1996

Fingerprint

Huntington Disease
Genetic Testing
Genetic Predisposition to Disease
Alcoholism
Alzheimer Disease
Testing
Research laboratories
Screening
Genes
Genetic Research
Twin Studies
Genetics

Keywords

  • Alcoholism
  • Genetics
  • Susceptibility

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Toxicology

Cite this

Issues in genetic testing for susceptibility to alcoholism : Lessons from Alzheimer's disease and Huntington's disease. / Quaid, Kimberly A.; Dinwiddie, Stephen H.; Michael Conneally, P.; Nurnberger, John.

In: Alcoholism: Clinical and Experimental Research, Vol. 20, No. 8, 1996, p. 1430-1437.

Research output: Contribution to journalArticle

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