Kinesins conventionally act as molecular motor proteins that translocate along microtubules. However, several kinesins also control microtubule polymerization dynamics. New work shows that the yeast kinesin-8 Kip3p has a unique combination of plus-end motor and plus-end depolymerase activities. These activities facilitate the positioning of the mitotic spindle at the cell cortex.
ASJC Scopus subject areas
- Cell Biology