Lack of association of a restriction fragment length polymorphism for serum amyloid P gene with reactive amyloidosis

Noam Harats, Barbara Kluve‐Beckerman, Martha Skinner, Murray Passo, Linda Quinn, Merrill D. Benson

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

The prevalence of a recently described restriction fragment length polymorphism using Msp I for the serum amyloid P gene was determined in 5 groups of patients. Patients with reactive (secondary) amyloidosis, juvenile rheumatoid arthritis, related inflammatory conditions, or juvenile rheumatoid arthritis with reactive amyloidosis, and healthy control subjects were found to be polymorphic for 8.8-kb and 5.6-kb gene fragments; they either had one or the other or both fragments. No significant differences were seen between these groups with relation to this polymorphism, and no correlation with the presence of reactive amyloidosis was observed.

Original languageEnglish (US)
Pages (from-to)1325-1327
Number of pages3
JournalArthritis & Rheumatism
Volume32
Issue number10
DOIs
StatePublished - Oct 1989

ASJC Scopus subject areas

  • Immunology and Allergy
  • Rheumatology
  • Immunology
  • Pharmacology (medical)

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