Lack of association of a restriction fragment length polymorphism for serum amyloid P gene with reactive amyloidosis

N. Harats, B. Kluve-Beckerman, M. Skinner, M. Passo, L. Quinn, Merrill Benson

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The prevalence of a recently described restriction fragment length polymorphism using Msp I for the serum amyloid P gene was determined in 5 groups of patients. Patients with reactive (secondary) amyloidosis, juvenile rheumatoid arthritis, related inflammatory conditions, or juvenile rheumatoid arthritis with reactive amyloidosis, and healthy control subjects were found to be polymorphic for 8.8-kb and 5.6-kb gene fragments; they either had one or the other or both fragments. No significant differences were seen between these groups with relation to this polymorphism, and no correlation with the presence of reactive amyloidosis was observed.

Original languageEnglish
Pages (from-to)1325-1327
Number of pages3
JournalArthritis and Rheumatism
Volume32
Issue number10
StatePublished - 1989

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Amyloidosis
Amyloid
Restriction Fragment Length Polymorphisms
Juvenile Arthritis
Serum
Genes
Healthy Volunteers

ASJC Scopus subject areas

  • Immunology
  • Rheumatology

Cite this

Lack of association of a restriction fragment length polymorphism for serum amyloid P gene with reactive amyloidosis. / Harats, N.; Kluve-Beckerman, B.; Skinner, M.; Passo, M.; Quinn, L.; Benson, Merrill.

In: Arthritis and Rheumatism, Vol. 32, No. 10, 1989, p. 1325-1327.

Research output: Contribution to journalArticle

Harats, N, Kluve-Beckerman, B, Skinner, M, Passo, M, Quinn, L & Benson, M 1989, 'Lack of association of a restriction fragment length polymorphism for serum amyloid P gene with reactive amyloidosis', Arthritis and Rheumatism, vol. 32, no. 10, pp. 1325-1327.
Harats, N. ; Kluve-Beckerman, B. ; Skinner, M. ; Passo, M. ; Quinn, L. ; Benson, Merrill. / Lack of association of a restriction fragment length polymorphism for serum amyloid P gene with reactive amyloidosis. In: Arthritis and Rheumatism. 1989 ; Vol. 32, No. 10. pp. 1325-1327.
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