Language before and after temporal lobectomy: Specificity of acute changes and relation to early risk factors

Andrew Saykin, P. Stafiniak, L. J. Robinson, K. A. Flannery, R. C. Gur, M. J. O'Connor, M. R. Sperling

Research output: Contribution to journalArticle

125 Citations (Scopus)

Abstract

We evaluated language functions in 154 patients with left hemisphere speech dominance undergoing anterior temporal lobectomy (ATL). Measures of phonemic and semantic fluency, confrontation naming, repetition, comprehension, and reading were administered before and 3 weeks postoperatively. Patients were grouped by focus (left, LT; right, RT) and presence of early risk factors for development of seizures (ER, early risk, ≤5 years; NER, no early risk): (LT-ER, n = 45; RT-ER, n = 49; LT-NER, n = 27; RT-NER, n = 33). Preoperatively, the LT group showed a selective naming deficit as compared with the RT group. Postoperatively only the LT-NER group showed significant overall decline in language. For this group, the change was attributable to a selective decline in naming as compared with other functions. These data indicate that there is a specific risk to naming after dominant ATL for adult temporal lobe epilepsy (TLE) patients with a left hemisphere focus and the absence of an early risk factor for the development of seizures.

Original languageEnglish (US)
Pages (from-to)1071-1077
Number of pages7
JournalEpilepsia
Volume36
Issue number11
DOIs
StatePublished - 1995
Externally publishedYes

Fingerprint

Anterior Temporal Lobectomy
Language
Seizures
Temporal Lobe Epilepsy
Semantics
Reading

Keywords

  • Aphasia
  • Epilepsy surgery
  • Language
  • Naming
  • Neuropsychology
  • Temporal lobe epilepsy

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Saykin, A., Stafiniak, P., Robinson, L. J., Flannery, K. A., Gur, R. C., O'Connor, M. J., & Sperling, M. R. (1995). Language before and after temporal lobectomy: Specificity of acute changes and relation to early risk factors. Epilepsia, 36(11), 1071-1077. https://doi.org/10.1111/j.1528-1157.1995.tb00464.x

Language before and after temporal lobectomy : Specificity of acute changes and relation to early risk factors. / Saykin, Andrew; Stafiniak, P.; Robinson, L. J.; Flannery, K. A.; Gur, R. C.; O'Connor, M. J.; Sperling, M. R.

In: Epilepsia, Vol. 36, No. 11, 1995, p. 1071-1077.

Research output: Contribution to journalArticle

Saykin, A, Stafiniak, P, Robinson, LJ, Flannery, KA, Gur, RC, O'Connor, MJ & Sperling, MR 1995, 'Language before and after temporal lobectomy: Specificity of acute changes and relation to early risk factors', Epilepsia, vol. 36, no. 11, pp. 1071-1077. https://doi.org/10.1111/j.1528-1157.1995.tb00464.x
Saykin, Andrew ; Stafiniak, P. ; Robinson, L. J. ; Flannery, K. A. ; Gur, R. C. ; O'Connor, M. J. ; Sperling, M. R. / Language before and after temporal lobectomy : Specificity of acute changes and relation to early risk factors. In: Epilepsia. 1995 ; Vol. 36, No. 11. pp. 1071-1077.
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