Large Sessile Adenomas Are Associated With a High Prevalence of Synchronous Advanced Adenomas

Wissam Mattar, Douglas Rex

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Background & Aims: The prevalence of synchronous neoplasia in patients with large sessile colorectal adenomas is uncertain. Methods: We conducted a retrospective single-center review of synchronous neoplastic findings in 190 consecutive patients with intact colons and single large sessile adenomas resected endoscopically. Synchronous polyps were those removed at the colonoscopy that discovered the large sessile adenoma or at any follow-up endoscopic examination within 12 months of discovery of the large sessile adenoma. Results: Seventy-five percent of patients had at least 1 synchronous adenoma, and the 190 patients had a mean of 4 synchronous adenomas. Thirty percent of patients had ≥1 synchronous advanced adenoma (adenoma ≥1 cm in size or with high-grade dysplasia or villous elements). There were a total of 116 synchronous advanced adenomas, including 89 adenomas 10-19 mm in size and 8 that were ≥20 mm in size. Conclusions: Colonoscopists should be aware that patients with large sessile adenomas have a high prevalence of synchronous advanced neoplasia. Prospective study of this issue is warranted.

Original languageEnglish
Pages (from-to)877-879
Number of pages3
JournalClinical Gastroenterology and Hepatology
Volume6
Issue number8
DOIs
StatePublished - Aug 2008

Fingerprint

Adenoma
Colonoscopy
Polyps
Neoplasms
Colon
Prospective Studies

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Large Sessile Adenomas Are Associated With a High Prevalence of Synchronous Advanced Adenomas. / Mattar, Wissam; Rex, Douglas.

In: Clinical Gastroenterology and Hepatology, Vol. 6, No. 8, 08.2008, p. 877-879.

Research output: Contribution to journalArticle

@article{382e801d24b84141a1e8f1e4cd18cdc1,
title = "Large Sessile Adenomas Are Associated With a High Prevalence of Synchronous Advanced Adenomas",
abstract = "Background & Aims: The prevalence of synchronous neoplasia in patients with large sessile colorectal adenomas is uncertain. Methods: We conducted a retrospective single-center review of synchronous neoplastic findings in 190 consecutive patients with intact colons and single large sessile adenomas resected endoscopically. Synchronous polyps were those removed at the colonoscopy that discovered the large sessile adenoma or at any follow-up endoscopic examination within 12 months of discovery of the large sessile adenoma. Results: Seventy-five percent of patients had at least 1 synchronous adenoma, and the 190 patients had a mean of 4 synchronous adenomas. Thirty percent of patients had ≥1 synchronous advanced adenoma (adenoma ≥1 cm in size or with high-grade dysplasia or villous elements). There were a total of 116 synchronous advanced adenomas, including 89 adenomas 10-19 mm in size and 8 that were ≥20 mm in size. Conclusions: Colonoscopists should be aware that patients with large sessile adenomas have a high prevalence of synchronous advanced neoplasia. Prospective study of this issue is warranted.",
author = "Wissam Mattar and Douglas Rex",
year = "2008",
month = "8",
doi = "10.1016/j.cgh.2008.04.012",
language = "English",
volume = "6",
pages = "877--879",
journal = "Clinical Gastroenterology and Hepatology",
issn = "1542-3565",
publisher = "W.B. Saunders Ltd",
number = "8",

}

TY - JOUR

T1 - Large Sessile Adenomas Are Associated With a High Prevalence of Synchronous Advanced Adenomas

AU - Mattar, Wissam

AU - Rex, Douglas

PY - 2008/8

Y1 - 2008/8

N2 - Background & Aims: The prevalence of synchronous neoplasia in patients with large sessile colorectal adenomas is uncertain. Methods: We conducted a retrospective single-center review of synchronous neoplastic findings in 190 consecutive patients with intact colons and single large sessile adenomas resected endoscopically. Synchronous polyps were those removed at the colonoscopy that discovered the large sessile adenoma or at any follow-up endoscopic examination within 12 months of discovery of the large sessile adenoma. Results: Seventy-five percent of patients had at least 1 synchronous adenoma, and the 190 patients had a mean of 4 synchronous adenomas. Thirty percent of patients had ≥1 synchronous advanced adenoma (adenoma ≥1 cm in size or with high-grade dysplasia or villous elements). There were a total of 116 synchronous advanced adenomas, including 89 adenomas 10-19 mm in size and 8 that were ≥20 mm in size. Conclusions: Colonoscopists should be aware that patients with large sessile adenomas have a high prevalence of synchronous advanced neoplasia. Prospective study of this issue is warranted.

AB - Background & Aims: The prevalence of synchronous neoplasia in patients with large sessile colorectal adenomas is uncertain. Methods: We conducted a retrospective single-center review of synchronous neoplastic findings in 190 consecutive patients with intact colons and single large sessile adenomas resected endoscopically. Synchronous polyps were those removed at the colonoscopy that discovered the large sessile adenoma or at any follow-up endoscopic examination within 12 months of discovery of the large sessile adenoma. Results: Seventy-five percent of patients had at least 1 synchronous adenoma, and the 190 patients had a mean of 4 synchronous adenomas. Thirty percent of patients had ≥1 synchronous advanced adenoma (adenoma ≥1 cm in size or with high-grade dysplasia or villous elements). There were a total of 116 synchronous advanced adenomas, including 89 adenomas 10-19 mm in size and 8 that were ≥20 mm in size. Conclusions: Colonoscopists should be aware that patients with large sessile adenomas have a high prevalence of synchronous advanced neoplasia. Prospective study of this issue is warranted.

UR - http://www.scopus.com/inward/record.url?scp=47949090923&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=47949090923&partnerID=8YFLogxK

U2 - 10.1016/j.cgh.2008.04.012

DO - 10.1016/j.cgh.2008.04.012

M3 - Article

VL - 6

SP - 877

EP - 879

JO - Clinical Gastroenterology and Hepatology

JF - Clinical Gastroenterology and Hepatology

SN - 1542-3565

IS - 8

ER -