Laryngomalacia and intra-neural striated muscle in an infant with the Freeman-Sheldon syndrome

Carlos A. Galliani, Bruce Matt

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Striated muscle cells within peripheral nerve trunks, a very rare dishistogenetic lesion, was found in the arytenoid submucosa of a ten and a half week old afroamerican male with the Freeman-Sheldon syndrome (craniocarpotarsal dysplasia) who presented with obstructive apnea. Laryngomalacia was confirmed endoscopically. Supraglottoplasty offered temporary relief of the obstruction. Our histopathological observation is puzzling and perhaps adds a new dimension to the appropriateness of 'dysplasia'. It remains to be seen whether the neuromuscular lesion is a coincidental finding, a mere curiosity or bears any clinical significance.

Original languageEnglish
Pages (from-to)243-248
Number of pages6
JournalInternational Journal of Pediatric Otorhinolaryngology
Volume25
Issue number1-3
DOIs
StatePublished - 1993

Fingerprint

Laryngomalacia
Striated Muscle
Exploratory Behavior
Apnea
Peripheral Nerves
Muscle Cells
Observation
Freeman-Sheldon syndrome

Keywords

  • Freeman-Sheldon syndrome
  • Heterotopic striated muscle
  • Laryngomalacia
  • Peripheral nerve

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Pediatrics, Perinatology, and Child Health
  • Pulmonary and Respiratory Medicine
  • Surgery

Cite this

Laryngomalacia and intra-neural striated muscle in an infant with the Freeman-Sheldon syndrome. / Galliani, Carlos A.; Matt, Bruce.

In: International Journal of Pediatric Otorhinolaryngology, Vol. 25, No. 1-3, 1993, p. 243-248.

Research output: Contribution to journalArticle

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