Late spontaneous disruption of a porcine xenograft mitral valve. Clinical, hemodynamic, echocardiographic, and pathological findings

J. W. Brown, J. M. Dunn, E. Spooner, M. M. Kirsh

Research output: Contribution to journalArticle

29 Scopus citations


A case is presented of failure of a Hancock porcine xenograft mitral prosthesis secondary to disruption of the prosthetic leaflets. Clinical, hemodynamic, and echocardiographic evidence of prosthetic dysfunction has been correlated with operative, pathological, and ultrastructural findings. Other instances of dysfunction of this prosthesis have been reviewed. Echocardiography should be routinely employed when the diagnosis of xenograft dysfunction is entertained.

Original languageEnglish (US)
Pages (from-to)606-611
Number of pages6
JournalJournal of Thoracic and Cardiovascular Surgery
Issue number4
StatePublished - Jan 1 1978


ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

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