Learning to roll before you stop and drop.

Joyce Marie Koenig, Mervin Yoder

Research output: Contribution to journalArticle

Abstract

In this issue of Blood, Sperandio and colleagues report the use of a unique intravital microscopic system to characterize an ontogenic process of blood cell and yolk sac endothelial maturation that is required to display full adult-type inflammation-induced leukocyte recruitment.(1) They report that murine fetal blood neutrophil rolling, adhesion, and extravasation from inflamed yolk sac vessels is apparent late in development, but that before embryonic day (E) 15, fetal blood neutrophils display little ability to roll or adhere to inflamed vascular endothelial cells. Similar behavior was displayed when fetal blood cells were tested in vitro on immobilized recombinant adhesion molecules.

Original languageEnglish (US)
Pages (from-to)4252-4254
Number of pages3
JournalBlood
Volume121
Issue number21
DOIs
StatePublished - May 23 2013

Fingerprint

Fetal Blood
Yolk Sac
Blood
Learning
Blood Cells
Neutrophils
Aptitude
Adhesion
Embryonic Development
Cells
Leukocytes
Endothelial Cells
Inflammation
Endothelial cells
Molecules

ASJC Scopus subject areas

  • Hematology
  • Biochemistry
  • Cell Biology
  • Immunology

Cite this

Learning to roll before you stop and drop. / Koenig, Joyce Marie; Yoder, Mervin.

In: Blood, Vol. 121, No. 21, 23.05.2013, p. 4252-4254.

Research output: Contribution to journalArticle

Koenig, Joyce Marie ; Yoder, Mervin. / Learning to roll before you stop and drop. In: Blood. 2013 ; Vol. 121, No. 21. pp. 4252-4254.
@article{a61ffa55be564683bdbd26c768556042,
title = "Learning to roll before you stop and drop.",
abstract = "In this issue of Blood, Sperandio and colleagues report the use of a unique intravital microscopic system to characterize an ontogenic process of blood cell and yolk sac endothelial maturation that is required to display full adult-type inflammation-induced leukocyte recruitment.(1) They report that murine fetal blood neutrophil rolling, adhesion, and extravasation from inflamed yolk sac vessels is apparent late in development, but that before embryonic day (E) 15, fetal blood neutrophils display little ability to roll or adhere to inflamed vascular endothelial cells. Similar behavior was displayed when fetal blood cells were tested in vitro on immobilized recombinant adhesion molecules.",
author = "Koenig, {Joyce Marie} and Mervin Yoder",
year = "2013",
month = "5",
day = "23",
doi = "10.1182/blood-2013-04-493502",
language = "English (US)",
volume = "121",
pages = "4252--4254",
journal = "Blood",
issn = "0006-4971",
publisher = "American Society of Hematology",
number = "21",

}

TY - JOUR

T1 - Learning to roll before you stop and drop.

AU - Koenig, Joyce Marie

AU - Yoder, Mervin

PY - 2013/5/23

Y1 - 2013/5/23

N2 - In this issue of Blood, Sperandio and colleagues report the use of a unique intravital microscopic system to characterize an ontogenic process of blood cell and yolk sac endothelial maturation that is required to display full adult-type inflammation-induced leukocyte recruitment.(1) They report that murine fetal blood neutrophil rolling, adhesion, and extravasation from inflamed yolk sac vessels is apparent late in development, but that before embryonic day (E) 15, fetal blood neutrophils display little ability to roll or adhere to inflamed vascular endothelial cells. Similar behavior was displayed when fetal blood cells were tested in vitro on immobilized recombinant adhesion molecules.

AB - In this issue of Blood, Sperandio and colleagues report the use of a unique intravital microscopic system to characterize an ontogenic process of blood cell and yolk sac endothelial maturation that is required to display full adult-type inflammation-induced leukocyte recruitment.(1) They report that murine fetal blood neutrophil rolling, adhesion, and extravasation from inflamed yolk sac vessels is apparent late in development, but that before embryonic day (E) 15, fetal blood neutrophils display little ability to roll or adhere to inflamed vascular endothelial cells. Similar behavior was displayed when fetal blood cells were tested in vitro on immobilized recombinant adhesion molecules.

UR - http://www.scopus.com/inward/record.url?scp=84880408299&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84880408299&partnerID=8YFLogxK

U2 - 10.1182/blood-2013-04-493502

DO - 10.1182/blood-2013-04-493502

M3 - Article

C2 - 23704046

AN - SCOPUS:84880408299

VL - 121

SP - 4252

EP - 4254

JO - Blood

JF - Blood

SN - 0006-4971

IS - 21

ER -