Leukemic meningitis complicating early stage chronic lymphocytic leukemia

Kathy Miller, Heidi Budke, Attilio Orazi

Research output: Contribution to journalArticle

28 Scopus citations


Central nervous system involvement in chronic lymphocytic leukemia is rare. We describe a patient with early stage chronic lymphocytic leukemia who developed visual loss and transient paresthesias. Lumbar puncture with cytology and flow cytometry documented leukemic meningitis, which responded to standard treatment, including cranial irradiation and intrathecal chemotherapy. We review the literature of all previously reported cases of brain or meningeal involvement by chronic lymphocytic leukemia and suggest that this complication may frequently go unrecognized.

Original languageEnglish (US)
Pages (from-to)524-527
Number of pages4
JournalArchives of Pathology and Laboratory Medicine
Issue number5
StatePublished - Jun 2 1997

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology

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