Linear lesions alter organization of atrial fibrillation

H. J. Sih, D. P. Zipes, E. J. Berbari

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations


Linear ablation lesions reduce the inducibility of atrial fibrillation (AF) in dogs. To test if organization of AF increases after ablation, magnitude-squared coherence was measured before and after circumscribing the right atrial appendage (RAA) with a linear radio-frequency ablation lesion. In 5 open-chest dogs, an 8x14 array of unipolar electrodes (2x4cm) mapped the epicardium of the right atrial free wall during AF. Coherence, which is bounded from 0 to 1, was measured over 4sec intervals. A site at the base of the RAA near the lesion (Ref1) and a site approximately 1.5cm distant to the lesion (Ref2) were chosen. For Ref1, average coherence increased by 0.084±0.036 (p<0.007). For Ref2, average coherence increased by 0.029±0.036 (p<0.15). Changes in coherence are significantly greater near the lesion as compared to that more distant to the lesion. A sufficient number of linear lesions may reduce the inducibility of AF by increasing its spatial organization.

Original languageEnglish
Title of host publicationComputers in Cardiology
Number of pages4
StatePublished - 1996

ASJC Scopus subject areas

  • Software
  • Cardiology and Cardiovascular Medicine

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    Sih, H. J., Zipes, D. P., & Berbari, E. J. (1996). Linear lesions alter organization of atrial fibrillation. In Computers in Cardiology (0 ed., Vol. 0, pp. 141-144)