Linear ablation lesions reduce the inducibility of atrial fibrillation (AF) in dogs. To test if organization of AF increases after ablation, magnitude-squared coherence was measured before and after circumscribing the right atrial appendage (RAA) with a linear radio-frequency ablation lesion. In 5 open-chest dogs, an 8x14 array of unipolar electrodes (2x4cm) mapped the epicardium of the right atrial free wall during AF. Coherence, which is bounded from 0 to 1, was measured over 4sec intervals. A site at the base of the RAA near the lesion (Ref1) and a site approximately 1.5cm distant to the lesion (Ref2) were chosen. For Ref1, average coherence increased by 0.084±0.036 (p<0.007). For Ref2, average coherence increased by 0.029±0.036 (p<0.15). Changes in coherence are significantly greater near the lesion as compared to that more distant to the lesion. A sufficient number of linear lesions may reduce the inducibility of AF by increasing its spatial organization.
|Title of host publication||Computers in Cardiology|
|Number of pages||4|
|State||Published - 1996|
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine