Localization of the gene for a syndrome of X-linked skeletal dysplasia and mental retardation to Xq27-qter

Stephen Dlouhy, J. C. Christian, J. L. Haines, P. M. Conneally, M. E. Hodes

Research output: Contribution to journalArticle

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Abstract

An Indiana family segregating a syndrome of X-linked mental retardation and skeletal anomalies was tested for linkage of the mutant gene to X-chromosome molecular markers. Lod scores of 3.27 and 3.06 (Θ-0) for the molecular probes St14-1 (DXS52) and Dx13 (DXS15), respectively, indicate that the disease gene is located in the terminal portion of Xq.

Original languageEnglish
Pages (from-to)136-139
Number of pages4
JournalHuman Genetics
Volume75
Issue number2
DOIs
StatePublished - Feb 1987

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Intellectual Disability
X-Linked Mental Retardation
Lod Score
Molecular Probes
Genetic Markers
Genes

ASJC Scopus subject areas

  • Genetics(clinical)
  • Genetics

Cite this

Localization of the gene for a syndrome of X-linked skeletal dysplasia and mental retardation to Xq27-qter. / Dlouhy, Stephen; Christian, J. C.; Haines, J. L.; Conneally, P. M.; Hodes, M. E.

In: Human Genetics, Vol. 75, No. 2, 02.1987, p. 136-139.

Research output: Contribution to journalArticle

Dlouhy, Stephen ; Christian, J. C. ; Haines, J. L. ; Conneally, P. M. ; Hodes, M. E. / Localization of the gene for a syndrome of X-linked skeletal dysplasia and mental retardation to Xq27-qter. In: Human Genetics. 1987 ; Vol. 75, No. 2. pp. 136-139.
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