Localization of the human cd59 gene by fluorescence in situ hybridization and pulsed-field gel electrophoresis

B. Heckl-Östreicher, S. Ragg, M. Drechsler, H. Scherthan, B. Royer-Pokora

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

We have localized the human CD59 gene encoding a membrane protein that inhibits cell lysis by the membrane-attack complex of the homologous complement system. Using chromosomal in situ suppression hybridization and pulsed-field gel electrophoresis, we mapped this gene to chromosome 11pl3, distal to the breakpoint of acute T-cell leukemia and proximal to the locus of the Wilms tumor gene on a 30-kb Sac II fragment.

Original languageEnglish (US)
Pages (from-to)144-146
Number of pages3
JournalCytogenetic and Genome Research
Volume63
Issue number3
DOIs
StatePublished - Jan 1 1993
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Genetics(clinical)

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