Localization of the human prealbumin gene to chromosome 18

Margaret R. Wallace, Susan L. Naylor, Barbara Kluve-Beckerman, George L. Long, Lisa McDonald, Thomas B. Shows, Merrill Benson

Research output: Contribution to journalArticle

85 Citations (Scopus)

Abstract

A human liver cDNA library was screened using an oligonucleotide probe based on the amino acid sequence of human prealbumin. The cDNA insert of one positive clone was sequenced and found to contain the entire coding sequence of human prealbumin plus untranslated 5′ and 3′ regions. This cDNA was used to probe DNA from a panel of mouse/human somatic cell hybrids. Only those hybrids containing human chromosome 18 showed the human-specific hybridization pattern, thereby localizing the human prealbumin gene to this chromosome.

Original languageEnglish
Pages (from-to)753-758
Number of pages6
JournalBiochemical and Biophysical Research Communications
Volume129
Issue number3
DOIs
StatePublished - Jun 28 1985

Fingerprint

Chromosomes, Human, Pair 18
Prealbumin
Chromosomes
Genes
Complementary DNA
Oligonucleotide Probes
5' Untranslated Regions
DNA Probes
3' Untranslated Regions
Gene Library
Liver
Amino Acids
Hybrid Cells
Human Chromosomes
Amino Acid Sequence
Clone Cells

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology

Cite this

Wallace, M. R., Naylor, S. L., Kluve-Beckerman, B., Long, G. L., McDonald, L., Shows, T. B., & Benson, M. (1985). Localization of the human prealbumin gene to chromosome 18. Biochemical and Biophysical Research Communications, 129(3), 753-758. https://doi.org/10.1016/0006-291X(85)91956-4

Localization of the human prealbumin gene to chromosome 18. / Wallace, Margaret R.; Naylor, Susan L.; Kluve-Beckerman, Barbara; Long, George L.; McDonald, Lisa; Shows, Thomas B.; Benson, Merrill.

In: Biochemical and Biophysical Research Communications, Vol. 129, No. 3, 28.06.1985, p. 753-758.

Research output: Contribution to journalArticle

Wallace, MR, Naylor, SL, Kluve-Beckerman, B, Long, GL, McDonald, L, Shows, TB & Benson, M 1985, 'Localization of the human prealbumin gene to chromosome 18', Biochemical and Biophysical Research Communications, vol. 129, no. 3, pp. 753-758. https://doi.org/10.1016/0006-291X(85)91956-4
Wallace MR, Naylor SL, Kluve-Beckerman B, Long GL, McDonald L, Shows TB et al. Localization of the human prealbumin gene to chromosome 18. Biochemical and Biophysical Research Communications. 1985 Jun 28;129(3):753-758. https://doi.org/10.1016/0006-291X(85)91956-4
Wallace, Margaret R. ; Naylor, Susan L. ; Kluve-Beckerman, Barbara ; Long, George L. ; McDonald, Lisa ; Shows, Thomas B. ; Benson, Merrill. / Localization of the human prealbumin gene to chromosome 18. In: Biochemical and Biophysical Research Communications. 1985 ; Vol. 129, No. 3. pp. 753-758.
@article{46c5fd9e977849bd8c7981c44c241552,
title = "Localization of the human prealbumin gene to chromosome 18",
abstract = "A human liver cDNA library was screened using an oligonucleotide probe based on the amino acid sequence of human prealbumin. The cDNA insert of one positive clone was sequenced and found to contain the entire coding sequence of human prealbumin plus untranslated 5′ and 3′ regions. This cDNA was used to probe DNA from a panel of mouse/human somatic cell hybrids. Only those hybrids containing human chromosome 18 showed the human-specific hybridization pattern, thereby localizing the human prealbumin gene to this chromosome.",
author = "Wallace, {Margaret R.} and Naylor, {Susan L.} and Barbara Kluve-Beckerman and Long, {George L.} and Lisa McDonald and Shows, {Thomas B.} and Merrill Benson",
year = "1985",
month = "6",
day = "28",
doi = "10.1016/0006-291X(85)91956-4",
language = "English",
volume = "129",
pages = "753--758",
journal = "Biochemical and Biophysical Research Communications",
issn = "0006-291X",
publisher = "Academic Press Inc.",
number = "3",

}

TY - JOUR

T1 - Localization of the human prealbumin gene to chromosome 18

AU - Wallace, Margaret R.

AU - Naylor, Susan L.

AU - Kluve-Beckerman, Barbara

AU - Long, George L.

AU - McDonald, Lisa

AU - Shows, Thomas B.

AU - Benson, Merrill

PY - 1985/6/28

Y1 - 1985/6/28

N2 - A human liver cDNA library was screened using an oligonucleotide probe based on the amino acid sequence of human prealbumin. The cDNA insert of one positive clone was sequenced and found to contain the entire coding sequence of human prealbumin plus untranslated 5′ and 3′ regions. This cDNA was used to probe DNA from a panel of mouse/human somatic cell hybrids. Only those hybrids containing human chromosome 18 showed the human-specific hybridization pattern, thereby localizing the human prealbumin gene to this chromosome.

AB - A human liver cDNA library was screened using an oligonucleotide probe based on the amino acid sequence of human prealbumin. The cDNA insert of one positive clone was sequenced and found to contain the entire coding sequence of human prealbumin plus untranslated 5′ and 3′ regions. This cDNA was used to probe DNA from a panel of mouse/human somatic cell hybrids. Only those hybrids containing human chromosome 18 showed the human-specific hybridization pattern, thereby localizing the human prealbumin gene to this chromosome.

UR - http://www.scopus.com/inward/record.url?scp=0022004564&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022004564&partnerID=8YFLogxK

U2 - 10.1016/0006-291X(85)91956-4

DO - 10.1016/0006-291X(85)91956-4

M3 - Article

C2 - 2990465

AN - SCOPUS:0022004564

VL - 129

SP - 753

EP - 758

JO - Biochemical and Biophysical Research Communications

JF - Biochemical and Biophysical Research Communications

SN - 0006-291X

IS - 3

ER -