Long-term effects of a community-based lifestyle intervention to prevent type 2 diabetes: The DEPLOY extension pilot study

Ronald T. Ackermann, Emily A. Finch, Helena M. Caffrey, Elaine R. Lipscomb, Laura M. Hays, Chandan Saha

Research output: Contribution to journalArticle

35 Scopus citations

Abstract

Objective: The US Diabetes Prevention Program (DPP) and other large trials internationally have shown that an intensive lifestyle intervention can reduce the development of type 2 diabetes. We evaluated long-term effects of a lower cost, group-based adaption of the DPP lifestyle intervention offered by the YMCA. Methods: Participants were adults with BMI ≥24 kg/m2 and random capillary blood glucose 6.1-11.1 mmol/L who had been previously enrolled in a cluster-randomized trial comparing a group-based DPP lifestyle intervention versus brief advice alone. Four to 12 months after completion of the initial trial, 72% of 92 participants enrolled in an extension study, and all were offered a group lifestyle maintenance program at the YMCA. Paired t-tests were used to assess within-group changes; ANCOVA with adjustment was used for between-group comparisons. Results: At 28 months, after both arms were offered the same 8-month lifestyle maintenance intervention, both arms had statistically significant weight losses compared to baseline (brief advice controls: 3.6%; 95% CI: 5.8 to 1.4; intensive lifestyle: 6.0%; 95% CI: 8.8 to 3.2). Participants initially assigned to the DPP also experienced significant improvements in blood pressure and total cholesterol. Discussion: The YMCA is a promising channel for dissemination of a low-cost model for lifestyle diabetes prevention. Future studies are needed to verify these findings.

Original languageEnglish (US)
Pages (from-to)279-290
Number of pages12
JournalChronic Illness
Volume7
Issue number4
DOIs
StatePublished - Dec 1 2011

Keywords

  • community research
  • diabetes mellitus
  • Prediabetic state
  • primary prevention
  • type 2
  • weight loss

ASJC Scopus subject areas

  • Medicine(all)
  • Health Policy

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