Long term effects of gastrocystoplasty in rats

L. W. Klee, D. M. Hoover, M. E. Mitchell, R. C. Rink

Research output: Contribution to journalArticle

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Abstract

Twenty prepubescent rats underwent microsurgical gastrocystoplasty by a technique which is described. An equal number of control rats had their bladders opened and closed. Rats were sacrificed at 16 to 18 months postoperatively. There were no differences in final weight, serum electrolytes, or renal function between the two groups. Prominent histopathologic changes of the bladder occurred in the gastrocystoplasty group. These changes included papillomas present in five of the 15 rats surviving long term. No significant changes occurred in the bladders of the control group of rats. Possible etiologies and the significance of the rats. Possible etiologies and the significance of the gastrocystoplasty related lesions are discussed.

Original languageEnglish
Pages (from-to)1283-1287
Number of pages5
JournalJournal of Urology
Volume144
Issue number5
StatePublished - 1990

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Urinary Bladder
Papilloma
Electrolytes
Kidney
Weights and Measures
Control Groups
Serum

ASJC Scopus subject areas

  • Urology

Cite this

Klee, L. W., Hoover, D. M., Mitchell, M. E., & Rink, R. C. (1990). Long term effects of gastrocystoplasty in rats. Journal of Urology, 144(5), 1283-1287.

Long term effects of gastrocystoplasty in rats. / Klee, L. W.; Hoover, D. M.; Mitchell, M. E.; Rink, R. C.

In: Journal of Urology, Vol. 144, No. 5, 1990, p. 1283-1287.

Research output: Contribution to journalArticle

Klee, LW, Hoover, DM, Mitchell, ME & Rink, RC 1990, 'Long term effects of gastrocystoplasty in rats', Journal of Urology, vol. 144, no. 5, pp. 1283-1287.
Klee LW, Hoover DM, Mitchell ME, Rink RC. Long term effects of gastrocystoplasty in rats. Journal of Urology. 1990;144(5):1283-1287.
Klee, L. W. ; Hoover, D. M. ; Mitchell, M. E. ; Rink, R. C. / Long term effects of gastrocystoplasty in rats. In: Journal of Urology. 1990 ; Vol. 144, No. 5. pp. 1283-1287.
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