Long-term fatigue behavior of compact bone at low strain magnitude and rate

M. B. Schaffler, E. L. Radin, David Burr

Research output: Contribution to journalArticle

151 Citations (Scopus)

Abstract

Fatigue behavior of compact bone at physiological strain ranges was examined in vitro. Standardized specimens of bovine compact bone were cyclically loaded in uniaxial tension of 0-1200 or 0-1500 microstrain for up to 13-37 million cycles to study the long-term fatigue properties. All specimens exhibited fatigue during the first several million cycles of loading, evidenced by a gradual decrease of specimen modulus during this initial loading period; mean modulus loss for all specimens was approximately 6%. After this initial stiffness loss, specimen modulus stabilized and did not change again for the duration of the loading. Osteonal bone specimens lost significantly more stiffness than primary bone specimens during the early loading history, but neither microstructural type progressed to fatigue failure. These data suggest that some fatigue of compact bone is a realistic expectation of the normal loading environment, but this fatigue does not progress to fatigue failure within a physiologically reasonable number of cycles when tested in vitro at strain magnitudes like those measured in living animals. Implications for fatigue/stress fractures in vivo are discussed.

Original languageEnglish
Pages (from-to)321-326
Number of pages6
JournalBone
Volume11
Issue number5
DOIs
StatePublished - 1990

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Fatigue
Stress Fractures
Bone and Bones
Cortical Bone
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Keywords

  • Compact bone
  • Fatigue
  • Physiological strains

ASJC Scopus subject areas

  • Physiology
  • Hematology

Cite this

Long-term fatigue behavior of compact bone at low strain magnitude and rate. / Schaffler, M. B.; Radin, E. L.; Burr, David.

In: Bone, Vol. 11, No. 5, 1990, p. 321-326.

Research output: Contribution to journalArticle

Schaffler, M. B. ; Radin, E. L. ; Burr, David. / Long-term fatigue behavior of compact bone at low strain magnitude and rate. In: Bone. 1990 ; Vol. 11, No. 5. pp. 321-326.
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