Long-term follow-up of solitary intracerebral juvenile xanthogranuloma: Case report and review of the literature

Daniel H. Fulkerson, Thomas G. Luerssen, Eyas M. Hattab, Daniel L. Kim, Jodi L. Smith

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

Juvenile xanthogranuloma is a benign, non-Langerhans-cell histiocytic infiltrate that typically presents as a solitary cutaneous lesion in childhood. There are reports of extracutanous involvement, including tumors in the central nervous system. A solitary, intraparenchymal tumor without skin manifestations is a rare event, with only 3 prior cases reported in the literature. Cerebral lesions have been associated with multifocal or systemic forms of the disease, with an occasionally fulminate clinical course. Considering the rarity of this tumor, it is unclear whether patients need adjuvant therapy after excision of a solitary intraparenchymal tumor. Previous reports suggested that complete excision of the lesion was curative; however long-term follow-up was not provided. This report illustrates a case of surgical excision of a solitary juvenile xanthogranuloma in an 8-year-old male with a 3-year follow-up period.

Original languageEnglish (US)
Pages (from-to)480-485
Number of pages6
JournalPediatric Neurosurgery
Volume44
Issue number6
DOIs
StatePublished - Jan 1 2009

Keywords

  • Histiocytosis
  • Juvenile xanthogranuloma
  • Pediatric brain tumor

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology
  • Surgery

Fingerprint Dive into the research topics of 'Long-term follow-up of solitary intracerebral juvenile xanthogranuloma: Case report and review of the literature'. Together they form a unique fingerprint.

  • Cite this