Long term study of the effect of rifampicin and isoniazid on vitamin D metabolism

S. E. Williams, A. G. Wardman, G. A. Taylor, Munro Peacock, N. J. Cooke

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Eight patients with tuberculosis were studied before, during and after 9 months treatment with rifampicin and isoniazid to assess the overall effect on vitamin D metabolism. No significant uniform change in either 1,25(OH)2D or 25 OH D nor in any of the other biochemistry measured occurred during the study. It seems unlikely that the combined effects of these drugs causes clinically significant derangement of vitamin D metabolism in patients treated over a 9 month period for tuberculosis.

Original languageEnglish (US)
Pages (from-to)49-54
Number of pages6
JournalTubercle
Volume66
Issue number1
DOIs
StatePublished - 1985
Externally publishedYes

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Isoniazid
Rifampin
Vitamin D
Tuberculosis
Biochemistry
Pharmaceutical Preparations
Therapeutics

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Long term study of the effect of rifampicin and isoniazid on vitamin D metabolism. / Williams, S. E.; Wardman, A. G.; Taylor, G. A.; Peacock, Munro; Cooke, N. J.

In: Tubercle, Vol. 66, No. 1, 1985, p. 49-54.

Research output: Contribution to journalArticle

Williams, S. E. ; Wardman, A. G. ; Taylor, G. A. ; Peacock, Munro ; Cooke, N. J. / Long term study of the effect of rifampicin and isoniazid on vitamin D metabolism. In: Tubercle. 1985 ; Vol. 66, No. 1. pp. 49-54.
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