Long term study of the effect of rifampicin and isoniazid on vitamin D metabolism

S. E. Williams, A. G. Wardman, G. A. Taylor, M. Peacock, N. J. Cooke

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Abstract

Eight patients with tuberculosis were studied before, during and after 9 months treatment with rifampicin and isoniazid to assess the overall effect on vitamin D metabolism. No significant uniform change in either 1,25(OH)2D or 25 OH D nor in any of the other biochemistry measured occurred during the study. It seems unlikely that the combined effects of these drugs causes clinically significant derangement of vitamin D metabolism in patients treated over a 9 month period for tuberculosis.

Original languageEnglish (US)
Pages (from-to)49-54
Number of pages6
JournalTubercle
Volume66
Issue number1
DOIs
StatePublished - Mar 1985

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ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Williams, S. E., Wardman, A. G., Taylor, G. A., Peacock, M., & Cooke, N. J. (1985). Long term study of the effect of rifampicin and isoniazid on vitamin D metabolism. Tubercle, 66(1), 49-54. https://doi.org/10.1016/0041-3879(85)90053-4