OBJECTIVE: To examine the contribution of cooccurring nonhead injuries to hazard of death after traumatic brain injury (TBI). PARTICIPANTS: A random sample of Olmsted County, Minnesota, residents with confirmed TBI from 1987 through 1999 was identified. DESIGN: Each case was assigned an age- and sex-matched, non-TBI "regular control" from the population. For "special cases" with accompanying nonhead injuries, 2 matched "special controls" with nonhead injuries of similar severity were assigned. MEASURES: Vital status was followed from baseline (ie, injury date for cases, comparable dates for controls) through 2008. Cases were compared first with regular controls and second with regular or special controls, depending on case type. RESULTS: In total, 1257 cases were identified (including 221 special cases). For both cases versus regular controls and cases versus regular or special controls, the hazard ratio was increased from baseline to 6 months (10.82 [2.86-40.89] and 7.13 [3.10-16.39], respectively) and from baseline through study end (2.92 [1.74-4.91] and 1.48 [1.09-2.02], respectively). Among 6-month survivors, the hazard ratio was increased for cases versus regular controls (1.43 [1.06-2.15]) but not for cases versus regular or special controls (1.05 [0.80-1.38]). CONCLUSIONS: Among 6-month survivors, accounting for nonhead injuries resulted in a nonsignificant effect of TBI on long-term mortality.
ASJC Scopus subject areas
- Clinical Neurology
- Physical Therapy, Sports Therapy and Rehabilitation
Long-term survival after traumatic brain injury : A population-based analysis controlled for nonhead trauma. / Brown, Allen W.; Leibson, Cynthia L.; Mandrekar, Jay; Ransom, Jeanine E.; Malec, James F.In: Journal of Head Trauma Rehabilitation, Vol. 29, No. 1, 01.2014.
Research output: Contribution to journal › Article
TY - JOUR
T1 - Long-term survival after traumatic brain injury
T2 - A population-based analysis controlled for nonhead trauma
AU - Brown, Allen W.
AU - Leibson, Cynthia L.
AU - Mandrekar, Jay
AU - Ransom, Jeanine E.
AU - Malec, James F.
PY - 2014/1
Y1 - 2014/1
N2 - Lippincott Williams and Wilkins.
AB - Lippincott Williams and Wilkins.
UR - http://www.scopus.com/inward/record.url?scp=84893016055&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84893016055&partnerID=8YFLogxK
U2 - 10.1097/HTR.0b013e318280d3e6
DO - 10.1097/HTR.0b013e318280d3e6
M3 - Article
C2 - 23381021
AN - SCOPUS:84893016055
VL - 29
JO - Journal of Head Trauma Rehabilitation
JF - Journal of Head Trauma Rehabilitation
SN - 0885-9701
IS - 1