Longer term clinical outcomes after radiofrequency therapy for refractory gastroesophageal reflux disease (GERD)

Peter Mavrelis, Ayman M. Abdel Aziz, Chris Rearick, Libby Richards, Gail McNulty, Glen Lehman

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Stretta for GERD refractory to PPI therapy has received very limited evaluation. Aim: To evaluate long-term efficacy of Stretta procedure used for management of refractory GERD. Methods: Thirty-two patients with refractory GERD to at least double doses PPI Underwent Stretta therapy. Mean follow-up time was 2.5 years. RESULTS: Stretta procedure was successfully completed in all patients with no serious complications. At baseline, HRQL while off medications was 26.3, compared with 17.1 at the end of the follow-up (p < 0.05). Mean HRQL on medications at baseline was 24.3, compared with 14.24 at the end of the follow-up (p < 0.05). At baseline all patients were taking at least double dose PPI daily. At the end of follow-up, two patients (6.25%) had discontinued their PPI's, and an additional 18 patients (56%) had reduced PPI doses by ≥50%. HRQL normalized while on medications in nine patients (28%). Conclusions: In this difficult patient population with refractory GERD symptoms, Stretta procedure was a feasible, safe and partially effective in decreasing symptoms and PPI use.

Original languageEnglish
Pages (from-to)73-80
Number of pages8
JournalPractical Gastroenterology
Volume31
Issue number10
StatePublished - Oct 2007

Fingerprint

Gastroesophageal Reflux
Therapeutics
Population

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Longer term clinical outcomes after radiofrequency therapy for refractory gastroesophageal reflux disease (GERD). / Mavrelis, Peter; Abdel Aziz, Ayman M.; Rearick, Chris; Richards, Libby; McNulty, Gail; Lehman, Glen.

In: Practical Gastroenterology, Vol. 31, No. 10, 10.2007, p. 73-80.

Research output: Contribution to journalArticle

Mavrelis, P, Abdel Aziz, AM, Rearick, C, Richards, L, McNulty, G & Lehman, G 2007, 'Longer term clinical outcomes after radiofrequency therapy for refractory gastroesophageal reflux disease (GERD)', Practical Gastroenterology, vol. 31, no. 10, pp. 73-80.
Mavrelis, Peter ; Abdel Aziz, Ayman M. ; Rearick, Chris ; Richards, Libby ; McNulty, Gail ; Lehman, Glen. / Longer term clinical outcomes after radiofrequency therapy for refractory gastroesophageal reflux disease (GERD). In: Practical Gastroenterology. 2007 ; Vol. 31, No. 10. pp. 73-80.
@article{4e834237303147e99d95664eea961692,
title = "Longer term clinical outcomes after radiofrequency therapy for refractory gastroesophageal reflux disease (GERD)",
abstract = "Stretta for GERD refractory to PPI therapy has received very limited evaluation. Aim: To evaluate long-term efficacy of Stretta procedure used for management of refractory GERD. Methods: Thirty-two patients with refractory GERD to at least double doses PPI Underwent Stretta therapy. Mean follow-up time was 2.5 years. RESULTS: Stretta procedure was successfully completed in all patients with no serious complications. At baseline, HRQL while off medications was 26.3, compared with 17.1 at the end of the follow-up (p < 0.05). Mean HRQL on medications at baseline was 24.3, compared with 14.24 at the end of the follow-up (p < 0.05). At baseline all patients were taking at least double dose PPI daily. At the end of follow-up, two patients (6.25{\%}) had discontinued their PPI's, and an additional 18 patients (56{\%}) had reduced PPI doses by ≥50{\%}. HRQL normalized while on medications in nine patients (28{\%}). Conclusions: In this difficult patient population with refractory GERD symptoms, Stretta procedure was a feasible, safe and partially effective in decreasing symptoms and PPI use.",
author = "Peter Mavrelis and {Abdel Aziz}, {Ayman M.} and Chris Rearick and Libby Richards and Gail McNulty and Glen Lehman",
year = "2007",
month = "10",
language = "English",
volume = "31",
pages = "73--80",
journal = "Practical Gastroenterology",
issn = "0277-4208",
publisher = "Shugar Publishing Inc.",
number = "10",

}

TY - JOUR

T1 - Longer term clinical outcomes after radiofrequency therapy for refractory gastroesophageal reflux disease (GERD)

AU - Mavrelis, Peter

AU - Abdel Aziz, Ayman M.

AU - Rearick, Chris

AU - Richards, Libby

AU - McNulty, Gail

AU - Lehman, Glen

PY - 2007/10

Y1 - 2007/10

N2 - Stretta for GERD refractory to PPI therapy has received very limited evaluation. Aim: To evaluate long-term efficacy of Stretta procedure used for management of refractory GERD. Methods: Thirty-two patients with refractory GERD to at least double doses PPI Underwent Stretta therapy. Mean follow-up time was 2.5 years. RESULTS: Stretta procedure was successfully completed in all patients with no serious complications. At baseline, HRQL while off medications was 26.3, compared with 17.1 at the end of the follow-up (p < 0.05). Mean HRQL on medications at baseline was 24.3, compared with 14.24 at the end of the follow-up (p < 0.05). At baseline all patients were taking at least double dose PPI daily. At the end of follow-up, two patients (6.25%) had discontinued their PPI's, and an additional 18 patients (56%) had reduced PPI doses by ≥50%. HRQL normalized while on medications in nine patients (28%). Conclusions: In this difficult patient population with refractory GERD symptoms, Stretta procedure was a feasible, safe and partially effective in decreasing symptoms and PPI use.

AB - Stretta for GERD refractory to PPI therapy has received very limited evaluation. Aim: To evaluate long-term efficacy of Stretta procedure used for management of refractory GERD. Methods: Thirty-two patients with refractory GERD to at least double doses PPI Underwent Stretta therapy. Mean follow-up time was 2.5 years. RESULTS: Stretta procedure was successfully completed in all patients with no serious complications. At baseline, HRQL while off medications was 26.3, compared with 17.1 at the end of the follow-up (p < 0.05). Mean HRQL on medications at baseline was 24.3, compared with 14.24 at the end of the follow-up (p < 0.05). At baseline all patients were taking at least double dose PPI daily. At the end of follow-up, two patients (6.25%) had discontinued their PPI's, and an additional 18 patients (56%) had reduced PPI doses by ≥50%. HRQL normalized while on medications in nine patients (28%). Conclusions: In this difficult patient population with refractory GERD symptoms, Stretta procedure was a feasible, safe and partially effective in decreasing symptoms and PPI use.

UR - http://www.scopus.com/inward/record.url?scp=41149138986&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=41149138986&partnerID=8YFLogxK

M3 - Article

VL - 31

SP - 73

EP - 80

JO - Practical Gastroenterology

JF - Practical Gastroenterology

SN - 0277-4208

IS - 10

ER -