Longer term clinical outcomes after radiofrequency therapy for refractory gastroesophageal reflux disease (GERD)

Peter Mavrelis, Ayman M. Abdel Aziz, Chris Rearick, Libby Richards, Gail McNulty, Glen A. Lehman

Research output: Contribution to journalArticle

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Stretta for GERD refractory to PPI therapy has received very limited evaluation. Aim: To evaluate long-term efficacy of Stretta procedure used for management of refractory GERD. Methods: Thirty-two patients with refractory GERD to at least double doses PPI Underwent Stretta therapy. Mean follow-up time was 2.5 years. RESULTS: Stretta procedure was successfully completed in all patients with no serious complications. At baseline, HRQL while off medications was 26.3, compared with 17.1 at the end of the follow-up (p < 0.05). Mean HRQL on medications at baseline was 24.3, compared with 14.24 at the end of the follow-up (p < 0.05). At baseline all patients were taking at least double dose PPI daily. At the end of follow-up, two patients (6.25%) had discontinued their PPI's, and an additional 18 patients (56%) had reduced PPI doses by ≥50%. HRQL normalized while on medications in nine patients (28%). Conclusions: In this difficult patient population with refractory GERD symptoms, Stretta procedure was a feasible, safe and partially effective in decreasing symptoms and PPI use.

Original languageEnglish (US)
Pages (from-to)73-80
Number of pages8
JournalPractical Gastroenterology
Issue number10
StatePublished - Oct 1 2007


ASJC Scopus subject areas

  • Gastroenterology

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