Longitudinal Effects of Medical Comorbidities on Functional Outcome and Life Satisfaction after Traumatic Brain Injury: An Individual Growth Curve Analysis of NIDILRR Traumatic Brain Injury Model System Data

James F. Malec, Jessica M. Ketchum, Flora Hammond, John D. Corrigan, Kristen Dams-O'Connor, Tessa Hart, Thomas Novack, Marie Dahdah, Gale G. Whiteneck, Jennifer Bogner

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Objective: To explore associations of specific physical and neuropsychiatric medical conditions to motor and cognitive functioning and life satisfaction over the first 10 years following traumatic brain injury (TBI). Setting: Telephone follow-up through 6 TBI Model System centers. Participants: In total, 404 individuals or proxies with TBI enrolled in the TBI Model System longitudinal study participating in 10-year follow-up. Design: Individual growth curve analysis. Main Measures: FIM Motor and Cognitive subscales, Satisfaction With Life Scales, and Medical and Mental Health Comorbidities Interview. Results: Hypertension, diabetes, cancers, rheumatoid arthritis, and anxiety negatively affected the trajectory of motor functioning over time. Diabetes, cancers, chronic bronchitis, anxiety, and depression negatively impacted cognitive functioning. Numerous neuropsychiatric conditions (sleep disorder, alcoholism, drug addiction, anxiety, panic attacks, posttraumatic stress disorder, depression, and bipolar disorder), as well as hypertension, liver disease, and cancers, diminished life satisfaction. Other medical conditions had a negative effect on functioning and satisfaction at specific follow-up periods. Conclusion: Natural recovery after TBI may include delayed onset of functional decline or early recovery, followed by progressive deterioration, and is negatively affected by medical comorbidities. Results contribute to the growing evidence that TBI is most appropriately treated as a chronic medical condition complicated by a variety of comorbid conditions.

Original languageEnglish (US)
JournalJournal of Head Trauma Rehabilitation
DOIs
StatePublished - Jan 1 2019

Fingerprint

Information Systems
Comorbidity
Growth
Anxiety
Depression
Hypertension
Panic Disorder
Chronic Bronchitis
Proxy
Liver Neoplasms
Post-Traumatic Stress Disorders
Bipolar Disorder
Telephone
Alcoholism
Substance-Related Disorders
Longitudinal Studies
Traumatic Brain Injury
Liver Diseases
Rheumatoid Arthritis
Neoplasms

Keywords

  • comorbidities
  • function
  • life satisfaction
  • medical conditions
  • outcomes
  • prevalence
  • rehabilitation
  • traumatic brain injury

ASJC Scopus subject areas

  • Physical Therapy, Sports Therapy and Rehabilitation
  • Rehabilitation
  • Clinical Neurology

Cite this

Longitudinal Effects of Medical Comorbidities on Functional Outcome and Life Satisfaction after Traumatic Brain Injury : An Individual Growth Curve Analysis of NIDILRR Traumatic Brain Injury Model System Data. / Malec, James F.; Ketchum, Jessica M.; Hammond, Flora; Corrigan, John D.; Dams-O'Connor, Kristen; Hart, Tessa; Novack, Thomas; Dahdah, Marie; Whiteneck, Gale G.; Bogner, Jennifer.

In: Journal of Head Trauma Rehabilitation, 01.01.2019.

Research output: Contribution to journalArticle

Malec, James F. ; Ketchum, Jessica M. ; Hammond, Flora ; Corrigan, John D. ; Dams-O'Connor, Kristen ; Hart, Tessa ; Novack, Thomas ; Dahdah, Marie ; Whiteneck, Gale G. ; Bogner, Jennifer. / Longitudinal Effects of Medical Comorbidities on Functional Outcome and Life Satisfaction after Traumatic Brain Injury : An Individual Growth Curve Analysis of NIDILRR Traumatic Brain Injury Model System Data. In: Journal of Head Trauma Rehabilitation. 2019.
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abstract = "Objective: To explore associations of specific physical and neuropsychiatric medical conditions to motor and cognitive functioning and life satisfaction over the first 10 years following traumatic brain injury (TBI). Setting: Telephone follow-up through 6 TBI Model System centers. Participants: In total, 404 individuals or proxies with TBI enrolled in the TBI Model System longitudinal study participating in 10-year follow-up. Design: Individual growth curve analysis. Main Measures: FIM Motor and Cognitive subscales, Satisfaction With Life Scales, and Medical and Mental Health Comorbidities Interview. Results: Hypertension, diabetes, cancers, rheumatoid arthritis, and anxiety negatively affected the trajectory of motor functioning over time. Diabetes, cancers, chronic bronchitis, anxiety, and depression negatively impacted cognitive functioning. Numerous neuropsychiatric conditions (sleep disorder, alcoholism, drug addiction, anxiety, panic attacks, posttraumatic stress disorder, depression, and bipolar disorder), as well as hypertension, liver disease, and cancers, diminished life satisfaction. Other medical conditions had a negative effect on functioning and satisfaction at specific follow-up periods. Conclusion: Natural recovery after TBI may include delayed onset of functional decline or early recovery, followed by progressive deterioration, and is negatively affected by medical comorbidities. Results contribute to the growing evidence that TBI is most appropriately treated as a chronic medical condition complicated by a variety of comorbid conditions.",
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