Long‐term corticosteriod treatment of myasthenia gravis: Report of 116 Patients

Robert M. Pascuzzi, H. Branch Coslett, T. R. Johns

Research output: Contribution to journalArticle

228 Scopus citations


One hundred sixteen patients, aged 8 to 82 years, with myasthenia gravis were treated with prednisone, 6o to 80 mg daily, until the onset of improvement, followed by lower‐dose alternate‐day therapy of several years' duration. Of all patients, 80.2%achived wither remission(27.6%) or marked improvement (52.6%). Moderate improvement occurred in 14.7%, and 5.2% showed no improvement. Increasing age correlated with a favorable outcome, but sex, duration of illness prior to treatment, severity and distribution of weaskness at the time of onset of treatment, and presence of thymoma were not factors in the response to therapy.

Original languageEnglish (US)
Pages (from-to)291-298
Number of pages8
JournalAnnals of Neurology
Issue number3
StatePublished - Mar 1984
Externally publishedYes

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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