Loss of sexual differentiation of rat hepatocytes in short-term culture.

J. E. Roepke, David Crabb

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We investigated the maintenance of alcohol dehydrogenase (ADH) and estrogen receptors in primary cultures of rat hepatocytes. Female hepatocytes partially lose ADH activity and completely lose estrogen receptors during 4 days in culture. Growth hormone, which induces both the enzyme and receptor in vivo, did not induce either in vitro.

Original languageEnglish
Pages (from-to)263-264
Number of pages2
JournalAlcohol and Alcoholism
VolumeSuppl 1
StatePublished - 1987

Fingerprint

Sex Differentiation
Alcohol Dehydrogenase
Estrogen Receptors
Rats
Hepatocytes
Growth Hormone
Maintenance
Enzymes
In Vitro Techniques

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Toxicology

Cite this

Loss of sexual differentiation of rat hepatocytes in short-term culture. / Roepke, J. E.; Crabb, David.

In: Alcohol and Alcoholism, Vol. Suppl 1, 1987, p. 263-264.

Research output: Contribution to journalArticle

@article{da874dff25da47de8e86a9e758a6f4f2,
title = "Loss of sexual differentiation of rat hepatocytes in short-term culture.",
abstract = "We investigated the maintenance of alcohol dehydrogenase (ADH) and estrogen receptors in primary cultures of rat hepatocytes. Female hepatocytes partially lose ADH activity and completely lose estrogen receptors during 4 days in culture. Growth hormone, which induces both the enzyme and receptor in vivo, did not induce either in vitro.",
author = "Roepke, {J. E.} and David Crabb",
year = "1987",
language = "English",
volume = "Suppl 1",
pages = "263--264",
journal = "Alcohol and Alcoholism",
issn = "0735-0414",
publisher = "Oxford University Press",

}

TY - JOUR

T1 - Loss of sexual differentiation of rat hepatocytes in short-term culture.

AU - Roepke, J. E.

AU - Crabb, David

PY - 1987

Y1 - 1987

N2 - We investigated the maintenance of alcohol dehydrogenase (ADH) and estrogen receptors in primary cultures of rat hepatocytes. Female hepatocytes partially lose ADH activity and completely lose estrogen receptors during 4 days in culture. Growth hormone, which induces both the enzyme and receptor in vivo, did not induce either in vitro.

AB - We investigated the maintenance of alcohol dehydrogenase (ADH) and estrogen receptors in primary cultures of rat hepatocytes. Female hepatocytes partially lose ADH activity and completely lose estrogen receptors during 4 days in culture. Growth hormone, which induces both the enzyme and receptor in vivo, did not induce either in vitro.

UR - http://www.scopus.com/inward/record.url?scp=0023464270&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023464270&partnerID=8YFLogxK

M3 - Article

VL - Suppl 1

SP - 263

EP - 264

JO - Alcohol and Alcoholism

JF - Alcohol and Alcoholism

SN - 0735-0414

ER -