Lung cancer surgery in the octogenarian

Keith S. Naunheim, Kenneth Kesler, S. A. D’ Orazio, A. C. Fiore, D. R. Judd

Research output: Contribution to journalArticle

86 Citations (Scopus)

Abstract

From 1981 through 1991, 40 patients 80 years of age or older underwentthoracotomy for curative resection of bronchogenic carcinoma. There were 22males and 18 females with a mean age of 82.7 years (range 80–88). In threepatients, the operation was aborted due to unexpected metastatic diseasediscovered at the time of thoracotomy. The remaining 37 patients underwent5 pneumonectomies, 26 lobectomies and 6 segmentectomies or wedgeresections. Three of these patients (1 pneumonectomy, 1 lobectomy, and 1wedge resection) underwent concomitant en bloc chest wall resection. Theoverall operative mortality rate (in hospital or within 30 days) was 15%(6/40) while there was a 16% mortality rate (6/37) for resected patients.Complications occurred in 18 of 40 patients (45%) but were major in only 12(30%). Major complications included respiratory insufficiency (6), pneumonia (4), prolonged air leak (2), stroke (1), urinary retentionprostatectomy (1), and one unexplained sudden death 2 weeks followingdischarge. Postoperative stay in the 34 operative survivors averaged 14 ±8.8 days (range 3–47). Univariate analysis revealed that neither gender, extent of lung resection, preoperative NYHA class, history of heart diseasenor chronic obstructive pulmonary disease (COPD) were predictive ofoperative mortality in the 37 patients undergoing lung resection. Age wasthe only predictor of mortality (survivors 82.2 ± 2.2, non-survivors 84.3± 2.6; P <0.05). The need for chest wall resection approached but didnot quite achieve significance (P <0.08). Actuarial survival for all 40patients at 1 and 3 years is 55% and 40%, respectively. Seventeen of 37 resected patients (46%) are still alive and all but 2 are in NYHA class I or II. These data suggest that 1) lung resection of bronchogenic carcinoma can be undertaken in the octogenarian although increased morbidity and mortality must be expected, 2) advanced age appears to be predictive of mortality, and 3) patients surviving hospitalization can expect reasonable survival with acceptable quality of life.

Original languageEnglish (US)
Pages (from-to)453-456
Number of pages4
JournalEuropean Journal of Cardio-thoracic Surgery
Volume8
Issue number9
DOIs
StatePublished - 1994

Fingerprint

Lung Neoplasms
Mortality
Pneumonectomy
Bronchogenic Carcinoma
Thoracic Wall
Lung
Survivors
Survival
Segmental Mastectomy
Thoracotomy
Sudden Death
Respiratory Insufficiency
Chronic Obstructive Pulmonary Disease
Pneumonia
Hospitalization
Stroke
Air
Quality of Life
Morbidity

Keywords

  • Elderly
  • Lung neoplasm
  • Octogenarian
  • Surgical therapy

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery
  • Pulmonary and Respiratory Medicine

Cite this

Naunheim, K. S., Kesler, K., D’ Orazio, S. A., Fiore, A. C., & Judd, D. R. (1994). Lung cancer surgery in the octogenarian. European Journal of Cardio-thoracic Surgery, 8(9), 453-456. https://doi.org/10.1016/1010-7940(94)90013-2

Lung cancer surgery in the octogenarian. / Naunheim, Keith S.; Kesler, Kenneth; D’ Orazio, S. A.; Fiore, A. C.; Judd, D. R.

In: European Journal of Cardio-thoracic Surgery, Vol. 8, No. 9, 1994, p. 453-456.

Research output: Contribution to journalArticle

Naunheim, KS, Kesler, K, D’ Orazio, SA, Fiore, AC & Judd, DR 1994, 'Lung cancer surgery in the octogenarian', European Journal of Cardio-thoracic Surgery, vol. 8, no. 9, pp. 453-456. https://doi.org/10.1016/1010-7940(94)90013-2
Naunheim, Keith S. ; Kesler, Kenneth ; D’ Orazio, S. A. ; Fiore, A. C. ; Judd, D. R. / Lung cancer surgery in the octogenarian. In: European Journal of Cardio-thoracic Surgery. 1994 ; Vol. 8, No. 9. pp. 453-456.
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