Magnesium kinetics in adolescent girls determined using stable isotopes: Effects of high and low calcium intake

Janice Sojka, Meryl Wastney, Steven Abrams, Sarah Froese Lewis, Berdine Martin, Connie Weaver, Munro Peacock

Research output: Contribution to journalArticle

36 Scopus citations

Abstract

Magnesium kinetics were measured in five adolescent girls who were participating in a calcium balance study. Two calcium levels were fed in a randomized crossover design. After an acclimation period, 26Mg was consumed orally and 25Mg was given intravenously, and then blood, urine, and feces were collected for 14 days. Total magnesium and percent enrichment were determined, and data were fitted to a eight-compartment model. There was no significant difference between high and low calcium intakes for any of the parameters examined. Mean values for control (800 mg/day) and high (1,800 mg/day) calcium intake were as follows: Mg intake, 305 ± 30 and 286 ± 9 mg/day; absorption (percent), 44 ± 7 and 39 ± 9; absorption (mg/day), 134 ± 35 and 110 ± 28; urinary excretion, 96 ± 22 and 101 ± 31 mg/day; fecal excretion, 175 ± 32 and 200 ± 11 mg/day; and magnesium balance, 13 ± 35 and -34 ± 48 mg/day, respectively. In conclusion, high calcium intake did not alter magnesium kinetics or balance in adolescent girls.

Original languageEnglish (US)
Pages (from-to)R710-R715
JournalAmerican Journal of Physiology - Regulatory Integrative and Comparative Physiology
Volume273
Issue number2 42-2
StatePublished - Oct 18 1997

Keywords

  • Kinetic modeling
  • Magnesium absorption
  • Magnesium excretion

ASJC Scopus subject areas

  • Physiology
  • Physiology (medical)

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