Magnetic Resonance Imaging: Clinical Correlation in 64 Patients With Multiple Sclerosis

James C. Stevens, Martin R. Farlow, Mary K. Edwards, Pao Lo Yu

Research output: Contribution to journalArticle

32 Scopus citations

Abstract

Sixty-four patients with possible, probable, or definite multiple sclerosis (McAlpine criteria) were clinically evaluated using the expanded disability status scale (EDSS) and Scripps neurologic rating scale (NRS). All were examined with a 0.15T magnetic resonance scanner using T2-and T1-weighted images. Correlations between EDSS and NRS scores and severity of disease detected on magnetic resonance imaging were determined. Significant correlations existed between EDSS and NRS with magnetic resonance ratings. Moderate correlations were observed in the motor, cerebellar, and brainstem subgroups of the clinical scales. Significant low correlations existed in the mood/mentation, vision (optic nerves), and bowel/bladder subgroups. Clinical and neuroimaging limitations may account for the lack of higher correlations. Significant correlations suggest the utility of magnetic resonance imaging in monitoring disease progression, and it may prove to be the technique of choice in following up patients with multiple sclerosis.

Original languageEnglish (US)
Pages (from-to)1145-1148
Number of pages4
JournalArchives of Neurology
Volume43
Issue number11
DOIs
StatePublished - Nov 1986

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology

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