Major Depression in Patients With Agoraphobia and Panic Disorder

Alan Breier, Dennis S. Charney, George R. Heninger

Research output: Contribution to journalArticle

249 Citations (Scopus)

Abstract

A review of the life-time occurrence of major depression, the temporal relationship of major depression to episodes of panic and agoraphobic disorders, and the severity of anxiety and depressive symptoms were determined In 60 patients with agoraphobia or panic disorder. Forty-one (68%) of the patients had a past or current episode of major depression, and 35 (85%) of these patients had endogenous-type major depression. Twenty patients (33%) had an episode of primary major depression, and an average of three years separated the end of primary major depression and the first panic attack. Secondary major depression occurred in 28 patients. Patients with a history of major depression had a more severe anxiety disorder. These data support the view that In a subgroup of patients, episodes of depression and panic anxiety disorder may be manifestations of a common underlying pathogenic process.

Original languageEnglish (US)
Pages (from-to)1129-1135
Number of pages7
JournalArchives of General Psychiatry
Volume41
Issue number12
DOIs
StatePublished - 1984
Externally publishedYes

Fingerprint

Agoraphobia
Panic Disorder
Depression
Anxiety Disorders
Panic
Depressive Disorder
Anxiety

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Psychiatry and Mental health

Cite this

Major Depression in Patients With Agoraphobia and Panic Disorder. / Breier, Alan; Charney, Dennis S.; Heninger, George R.

In: Archives of General Psychiatry, Vol. 41, No. 12, 1984, p. 1129-1135.

Research output: Contribution to journalArticle

Breier, Alan ; Charney, Dennis S. ; Heninger, George R. / Major Depression in Patients With Agoraphobia and Panic Disorder. In: Archives of General Psychiatry. 1984 ; Vol. 41, No. 12. pp. 1129-1135.
@article{d1f980fc391c464c83c1ea76f5e7c7cf,
title = "Major Depression in Patients With Agoraphobia and Panic Disorder",
abstract = "A review of the life-time occurrence of major depression, the temporal relationship of major depression to episodes of panic and agoraphobic disorders, and the severity of anxiety and depressive symptoms were determined In 60 patients with agoraphobia or panic disorder. Forty-one (68{\%}) of the patients had a past or current episode of major depression, and 35 (85{\%}) of these patients had endogenous-type major depression. Twenty patients (33{\%}) had an episode of primary major depression, and an average of three years separated the end of primary major depression and the first panic attack. Secondary major depression occurred in 28 patients. Patients with a history of major depression had a more severe anxiety disorder. These data support the view that In a subgroup of patients, episodes of depression and panic anxiety disorder may be manifestations of a common underlying pathogenic process.",
author = "Alan Breier and Charney, {Dennis S.} and Heninger, {George R.}",
year = "1984",
doi = "10.1001/archpsyc.1984.01790230015002",
language = "English (US)",
volume = "41",
pages = "1129--1135",
journal = "JAMA Psychiatry",
issn = "2168-622X",
publisher = "American Medical Association",
number = "12",

}

TY - JOUR

T1 - Major Depression in Patients With Agoraphobia and Panic Disorder

AU - Breier, Alan

AU - Charney, Dennis S.

AU - Heninger, George R.

PY - 1984

Y1 - 1984

N2 - A review of the life-time occurrence of major depression, the temporal relationship of major depression to episodes of panic and agoraphobic disorders, and the severity of anxiety and depressive symptoms were determined In 60 patients with agoraphobia or panic disorder. Forty-one (68%) of the patients had a past or current episode of major depression, and 35 (85%) of these patients had endogenous-type major depression. Twenty patients (33%) had an episode of primary major depression, and an average of three years separated the end of primary major depression and the first panic attack. Secondary major depression occurred in 28 patients. Patients with a history of major depression had a more severe anxiety disorder. These data support the view that In a subgroup of patients, episodes of depression and panic anxiety disorder may be manifestations of a common underlying pathogenic process.

AB - A review of the life-time occurrence of major depression, the temporal relationship of major depression to episodes of panic and agoraphobic disorders, and the severity of anxiety and depressive symptoms were determined In 60 patients with agoraphobia or panic disorder. Forty-one (68%) of the patients had a past or current episode of major depression, and 35 (85%) of these patients had endogenous-type major depression. Twenty patients (33%) had an episode of primary major depression, and an average of three years separated the end of primary major depression and the first panic attack. Secondary major depression occurred in 28 patients. Patients with a history of major depression had a more severe anxiety disorder. These data support the view that In a subgroup of patients, episodes of depression and panic anxiety disorder may be manifestations of a common underlying pathogenic process.

UR - http://www.scopus.com/inward/record.url?scp=0021689135&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021689135&partnerID=8YFLogxK

U2 - 10.1001/archpsyc.1984.01790230015002

DO - 10.1001/archpsyc.1984.01790230015002

M3 - Article

VL - 41

SP - 1129

EP - 1135

JO - JAMA Psychiatry

JF - JAMA Psychiatry

SN - 2168-622X

IS - 12

ER -