Malignant germ cell tumors

Research output: Chapter in Book/Report/Conference proceedingChapter

5 Scopus citations


Germ cell tumors are a relatively uncommon group of neoplasms which can have a variety of presentations affecting the fetus, infant, child, and adolescent. They are interesting for several reasons: in children the extragonadal site predominates compared with gonadal locations; the most common malignant histology is yolk sac tumor which has alpha fetoprotein as a sensitive marker; although in the past these tumors have had a poor prognosis they have been noted with excellent survival in the era of cooperative group trials utilizing cisplatin, etoposide, and bleomycin; and, based on the effectiveness of chemotherapy, neoadjuvant therapy followed by surgery is indicated to avoid excision of normal structures in unresectable cases.

Original languageEnglish (US)
Title of host publicationThe Surgery of Childhood Tumors
PublisherSpringer Berlin Heidelberg
Number of pages11
ISBN (Print)9783540297338
StatePublished - Dec 1 2008

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Rescorla, F. J. (2008). Malignant germ cell tumors. In The Surgery of Childhood Tumors (pp. 261-271). Springer Berlin Heidelberg.