Malignant germ cell tumors

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Pediatric germ cell tumors are relatively uncommon tumors which present at unusual sites in infancy in childhood. Most are benign and in the neonate and infants the extragonadal site predominates whereas in adolescence the gonadal site predominates. The clinical presentation is varied and is dependent upon the effect of the location and size of the tumor on adjacent structures. In the current area, primary resection when feasible is the treatment of choice, with low stage tumors usually requiring only surgery. Advanced stage tumors often require neoadjuvant chemotherapy with delayed surgical resection. The advent of cisplatin based therapy has markedly improved survival for children affected with malignant germ cell tumors.

Original languageEnglish (US)
Title of host publicationThe Surgery of Childhood Tumors
PublisherSpringer Berlin Heidelberg
Pages333-344
Number of pages12
ISBN (Electronic)9783662485903
ISBN (Print)9783662485880
DOIs
StatePublished - Jan 1 2016

Keywords

  • Extragonadal tumors
  • Germ cell tumors
  • Gonadal tumors
  • Testes and ovaries

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Rescorla, F. (2016). Malignant germ cell tumors. In The Surgery of Childhood Tumors (pp. 333-344). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-662-48590-3_19