Malignant melanoma with metastasis to adenocarcinoma of the prostate

David J. Grignon, Jae Y. Ro, Alberto G. Ayala

Research output: Contribution to journalArticle

22 Scopus citations

Abstract

Tumor‐to‐tumor metastases are uncommon despite the fact that the presence of two or more malignancies in a single patient is not a rare occurrence. The most frequent donor tumors are the lung, prostate, and thyroid gland, whereas renal cell carcinoma is by far the most common recipient. In this report we describe a patient dying of metastatic malignant melanoma and locally advanced prostate cancer in which the melanoma metastasized to the prostatic adenocarcinoma. The prostatic primary was well differentiated and stained positively with prostate‐specific antigen and prostatic acid phosphatase, whereas the melanoma contained abundant melanin pigment and stained positively for S‐100 protein. This is the second reported instance of prostatic carcinoma as the recipient in a case of tumor‐to‐tumor metastases and the first in the English language literature.

Original languageEnglish (US)
Pages (from-to)196-198
Number of pages3
JournalCancer
Volume63
Issue number1
DOIs
StatePublished - Jan 1 1989

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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