Management of Difficult Cases of Autoimmune Hepatitis

Craig Lammert, Veronica M. Loy, Kiyoko Oshima, Samer Gawrieh

Research output: Contribution to journalReview article

5 Citations (Scopus)

Abstract

Autoimmune hepatitis (AIH) is a complex autoimmune disease characterized by immune-mediated destruction of hepatic parenchyma which can result in cirrhosis, liver failure, and death. Current American Association for the Study of Liver Diseases (AASLD) and European Association for the Study of Liver (EASL) guidelines recommend corticosteroids alone or in combination with azathioprine as first-line treatment strategies. However, a significant proportion of patients may not be able to tolerate or achieve complete biochemical response with these options. In this article, we discuss approaches to these patients and other challenging AIH patient groups such as the asymptomatic, pregnant, elderly, and liver transplant recipients.

Original languageEnglish (US)
Pages (from-to)9
Number of pages1
JournalCurrent Gastroenterology Reports
Volume18
Issue number2
DOIs
StatePublished - Feb 1 2016

Fingerprint

Autoimmune Hepatitis
Case Management
Liver
Liver Failure
Azathioprine
Autoimmune Diseases
Adrenal Cortex Hormones
Fibrosis
Guidelines
Therapeutics

Keywords

  • Autoimmune hepatitis
  • Cirrhosis
  • Liver transplantation
  • Nonstandard treatment
  • Pregnancy
  • Refractory

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Management of Difficult Cases of Autoimmune Hepatitis. / Lammert, Craig; Loy, Veronica M.; Oshima, Kiyoko; Gawrieh, Samer.

In: Current Gastroenterology Reports, Vol. 18, No. 2, 01.02.2016, p. 9.

Research output: Contribution to journalReview article

Lammert, Craig ; Loy, Veronica M. ; Oshima, Kiyoko ; Gawrieh, Samer. / Management of Difficult Cases of Autoimmune Hepatitis. In: Current Gastroenterology Reports. 2016 ; Vol. 18, No. 2. pp. 9.
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