Management of Diminutive Colon Polyps Based on Endoluminal Imaging

David Lieberman, Joel Brill, Marcia Canto, Daniel DeMarco, Brian Fennerty, Neil Gupta, Loren Laine, Charles Lightdale, Elizabeth Montgomery, Robert Odze, Douglas Rex, Prateek Sharma, Michael Kochman, Jeffrey Tokar

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Diminutive colon polyps, defined as 5 mm or less, are encountered increasingly at colonoscopy. The risk of serious pathology in such polyps is low. There is a risk and cost of resecting all such polyps and sending tissue for pathologic evaluation. Enhancement of endoluminal imaging may enable discrimination of neoplastic vs non-neoplastic polyps. If this discrimination can be performed accurately with high confidence, it may be possible to either resect and discard diminutive adenomas, or inspect and do-not-resect diminutive hyperplastic polyps. In 2011, an expert group recommended thresholds of 90% negative predictive value for adenomas, and 90% accuracy in predicting appropriate surveillance intervals. Since 2011, criteria for polyp discrimination have been published and validated by experts and nonexperts. In vivo studies have been performed to compare endoscopic impression and pathologic diagnosis. An expert panel was convened in late 2014 to review the literature to determine if the proposed thresholds for discrimination can be attained and to recommend the next steps for introducing changes in clinical practice. We conclude that threshold levels can be achieved with several endoscopic image enhancements. The next steps to implementation of practice change include acquiring data on training and competence, determining best practices for auditing performance, understanding patient education needs, and the potential cost benefit of such changes.

Original languageEnglish (US)
Pages (from-to)1860-1866
Number of pages7
JournalClinical Gastroenterology and Hepatology
Volume13
Issue number11
DOIs
StatePublished - Nov 1 2015

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Polyps
Colon
Adenoma
Image Enhancement
Patient Education
Colonoscopy
Practice Guidelines
Mental Competency
Cost-Benefit Analysis
Pathology
Costs and Cost Analysis

Keywords

  • Adenomatous Polyp
  • Colonoscopy
  • Hyperplastic Polyp

ASJC Scopus subject areas

  • Gastroenterology
  • Hepatology

Cite this

Lieberman, D., Brill, J., Canto, M., DeMarco, D., Fennerty, B., Gupta, N., ... Tokar, J. (2015). Management of Diminutive Colon Polyps Based on Endoluminal Imaging. Clinical Gastroenterology and Hepatology, 13(11), 1860-1866. https://doi.org/10.1016/j.cgh.2015.07.011

Management of Diminutive Colon Polyps Based on Endoluminal Imaging. / Lieberman, David; Brill, Joel; Canto, Marcia; DeMarco, Daniel; Fennerty, Brian; Gupta, Neil; Laine, Loren; Lightdale, Charles; Montgomery, Elizabeth; Odze, Robert; Rex, Douglas; Sharma, Prateek; Kochman, Michael; Tokar, Jeffrey.

In: Clinical Gastroenterology and Hepatology, Vol. 13, No. 11, 01.11.2015, p. 1860-1866.

Research output: Contribution to journalArticle

Lieberman, D, Brill, J, Canto, M, DeMarco, D, Fennerty, B, Gupta, N, Laine, L, Lightdale, C, Montgomery, E, Odze, R, Rex, D, Sharma, P, Kochman, M & Tokar, J 2015, 'Management of Diminutive Colon Polyps Based on Endoluminal Imaging', Clinical Gastroenterology and Hepatology, vol. 13, no. 11, pp. 1860-1866. https://doi.org/10.1016/j.cgh.2015.07.011
Lieberman D, Brill J, Canto M, DeMarco D, Fennerty B, Gupta N et al. Management of Diminutive Colon Polyps Based on Endoluminal Imaging. Clinical Gastroenterology and Hepatology. 2015 Nov 1;13(11):1860-1866. https://doi.org/10.1016/j.cgh.2015.07.011
Lieberman, David ; Brill, Joel ; Canto, Marcia ; DeMarco, Daniel ; Fennerty, Brian ; Gupta, Neil ; Laine, Loren ; Lightdale, Charles ; Montgomery, Elizabeth ; Odze, Robert ; Rex, Douglas ; Sharma, Prateek ; Kochman, Michael ; Tokar, Jeffrey. / Management of Diminutive Colon Polyps Based on Endoluminal Imaging. In: Clinical Gastroenterology and Hepatology. 2015 ; Vol. 13, No. 11. pp. 1860-1866.
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