Management of experimental globe perforation during strabismus surgery

Derek T. Sprunger, Stephen R. Klapper, Jose M. Bonnin, John T. Minturn

Research output: Contribution to journalArticle

13 Scopus citations


Background: The incidence of potentially vision-threatening globe perforation during strabismus surgery is reportedly between less then 1% and 12% of cases. Optimal treatment of globe perforation is not known; however, traditionally it has been treated with cryotherapy at the time of surgery or observation without treatment. The indirect-ophthalmoscope-directed diode laser may provide a safe and effective alternative treatment. Methods: We perforated the globes of six adult Dutch rabbits (12 eyes) and treated four eyes with cryotherapy and four with diode laser; the remaining four were not treated. Results: Histologic examination of the untreated eyes revealed a cellular reaction around the polyglactin suture that formed a non-uniform chorioretinal adhesion. The cryotherapy eyes had a tenuous chorioretinal adhesion and retinal pigment epithelium (RPE) cells in the vitreous on several sections. The laser-treated eyes had a firm, wide chorioretinal adhesion, with minimal tissue disruption and no release of RPE cells. No complications occurred. Conclusion: We conclude that indirect-ophthalmoscope- directed diode laser retinopexy was safe and efficacious for globe perforation during strabismus surgery on rabbits and could be expected to be useful in humans.

Original languageEnglish (US)
Pages (from-to)140-143
Number of pages4
JournalJournal of Pediatric Ophthalmology and Strabismus
Issue number3
StatePublished - May 1 1996

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Ophthalmology

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