Management of Glaucoma in Pregnancy

Sunu Mathew, Alon Harris, Colin M. Ridenour, Barbara M. Wirostko, Kendall M. Burgett, Molly D. Scripture, Brent Siesky

Research output: Contribution to journalArticle

Abstract

Management of glaucoma during pregnancy represents a challenge for the physician. Important disease and patient health decisions begin even prior to conception and continue throughout pregnancy and breastfeeding. Data on this topic is limited due to ethical and legal constraints and challenges of conducting large, prospective, and randomized clinical trials on this patient population. Our review suggests that individually, intraocular pressure is lower in a pregnant woman when compared to a non-pregnant woman. Importantly, the medical management of glaucoma during pregnancy poses special challenges due to the possibility of adverse effects of medications on the fetus and newborn. Laser trabeculoplasty and traditional filtration surgery, as well as minimally invasive glaucoma surgery, represent non-drug management options. Thus, managing glaucoma in pregnancy is a delicate balance between treatment to prevent damage to the optic nerve in the mother and avoidance of interventions potentially harmful to the fetus. This literature review of published individual and population-based studies was performed in order to explore current knowledge and guidelines in the management of glaucoma in pregnancy.

Original languageEnglish (US)
JournalJournal of Glaucoma
DOIs
StatePublished - Jan 1 2019

Fingerprint

Glaucoma
Pregnancy
Fetus
Filtering Surgery
Trabeculectomy
Minimally Invasive Surgical Procedures
Optic Nerve
Breast Feeding
Intraocular Pressure
Population
Pregnant Women
Lasers
Randomized Controlled Trials
Mothers
Newborn Infant
Guidelines
Physicians
Health
Therapeutics

Keywords

  • anti-glaucoma medications
  • glaucoma
  • intraocular pressure
  • lactation
  • pregnancy

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Mathew, S., Harris, A., Ridenour, C. M., Wirostko, B. M., Burgett, K. M., Scripture, M. D., & Siesky, B. (2019). Management of Glaucoma in Pregnancy. Journal of Glaucoma. https://doi.org/10.1097/IJG.0000000000001324

Management of Glaucoma in Pregnancy. / Mathew, Sunu; Harris, Alon; Ridenour, Colin M.; Wirostko, Barbara M.; Burgett, Kendall M.; Scripture, Molly D.; Siesky, Brent.

In: Journal of Glaucoma, 01.01.2019.

Research output: Contribution to journalArticle

Mathew S, Harris A, Ridenour CM, Wirostko BM, Burgett KM, Scripture MD et al. Management of Glaucoma in Pregnancy. Journal of Glaucoma. 2019 Jan 1. https://doi.org/10.1097/IJG.0000000000001324
Mathew, Sunu ; Harris, Alon ; Ridenour, Colin M. ; Wirostko, Barbara M. ; Burgett, Kendall M. ; Scripture, Molly D. ; Siesky, Brent. / Management of Glaucoma in Pregnancy. In: Journal of Glaucoma. 2019.
@article{dac3df6896a9436aae3832380f6b3c6c,
title = "Management of Glaucoma in Pregnancy",
abstract = "Management of glaucoma during pregnancy represents a challenge for the physician. Important disease and patient health decisions begin even prior to conception and continue throughout pregnancy and breastfeeding. Data on this topic is limited due to ethical and legal constraints and challenges of conducting large, prospective, and randomized clinical trials on this patient population. Our review suggests that individually, intraocular pressure is lower in a pregnant woman when compared to a non-pregnant woman. Importantly, the medical management of glaucoma during pregnancy poses special challenges due to the possibility of adverse effects of medications on the fetus and newborn. Laser trabeculoplasty and traditional filtration surgery, as well as minimally invasive glaucoma surgery, represent non-drug management options. Thus, managing glaucoma in pregnancy is a delicate balance between treatment to prevent damage to the optic nerve in the mother and avoidance of interventions potentially harmful to the fetus. This literature review of published individual and population-based studies was performed in order to explore current knowledge and guidelines in the management of glaucoma in pregnancy.",
keywords = "anti-glaucoma medications, glaucoma, intraocular pressure, lactation, pregnancy",
author = "Sunu Mathew and Alon Harris and Ridenour, {Colin M.} and Wirostko, {Barbara M.} and Burgett, {Kendall M.} and Scripture, {Molly D.} and Brent Siesky",
year = "2019",
month = "1",
day = "1",
doi = "10.1097/IJG.0000000000001324",
language = "English (US)",
journal = "Journal of Glaucoma",
issn = "1057-0829",
publisher = "Lippincott Williams and Wilkins",

}

TY - JOUR

T1 - Management of Glaucoma in Pregnancy

AU - Mathew, Sunu

AU - Harris, Alon

AU - Ridenour, Colin M.

AU - Wirostko, Barbara M.

AU - Burgett, Kendall M.

AU - Scripture, Molly D.

AU - Siesky, Brent

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Management of glaucoma during pregnancy represents a challenge for the physician. Important disease and patient health decisions begin even prior to conception and continue throughout pregnancy and breastfeeding. Data on this topic is limited due to ethical and legal constraints and challenges of conducting large, prospective, and randomized clinical trials on this patient population. Our review suggests that individually, intraocular pressure is lower in a pregnant woman when compared to a non-pregnant woman. Importantly, the medical management of glaucoma during pregnancy poses special challenges due to the possibility of adverse effects of medications on the fetus and newborn. Laser trabeculoplasty and traditional filtration surgery, as well as minimally invasive glaucoma surgery, represent non-drug management options. Thus, managing glaucoma in pregnancy is a delicate balance between treatment to prevent damage to the optic nerve in the mother and avoidance of interventions potentially harmful to the fetus. This literature review of published individual and population-based studies was performed in order to explore current knowledge and guidelines in the management of glaucoma in pregnancy.

AB - Management of glaucoma during pregnancy represents a challenge for the physician. Important disease and patient health decisions begin even prior to conception and continue throughout pregnancy and breastfeeding. Data on this topic is limited due to ethical and legal constraints and challenges of conducting large, prospective, and randomized clinical trials on this patient population. Our review suggests that individually, intraocular pressure is lower in a pregnant woman when compared to a non-pregnant woman. Importantly, the medical management of glaucoma during pregnancy poses special challenges due to the possibility of adverse effects of medications on the fetus and newborn. Laser trabeculoplasty and traditional filtration surgery, as well as minimally invasive glaucoma surgery, represent non-drug management options. Thus, managing glaucoma in pregnancy is a delicate balance between treatment to prevent damage to the optic nerve in the mother and avoidance of interventions potentially harmful to the fetus. This literature review of published individual and population-based studies was performed in order to explore current knowledge and guidelines in the management of glaucoma in pregnancy.

KW - anti-glaucoma medications

KW - glaucoma

KW - intraocular pressure

KW - lactation

KW - pregnancy

UR - http://www.scopus.com/inward/record.url?scp=85068771740&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85068771740&partnerID=8YFLogxK

U2 - 10.1097/IJG.0000000000001324

DO - 10.1097/IJG.0000000000001324

M3 - Article

C2 - 31283700

AN - SCOPUS:85068771740

JO - Journal of Glaucoma

JF - Journal of Glaucoma

SN - 1057-0829

ER -