Management of patients with diabetes and CKD:  conclusions from a “Kidney Disease: Improving Global Outcomes” (KDIGO) Controversies Conference

Vlado Perkovic, Rajiv Agarwal, Paola Fioretto, Brenda R. Hemmelgarn, Adeera Levin, Merlin C. Thomas, Christoph Wanner, Bertram L. Kasiske, David C. Wheeler, Per Henrik Groop, George L. Bakris, Mark E. Cooper, Dong Wan Chae, Michael H. Davidson, Ian H. de Boer, Dick de Zeeuw, Alessia Fornoni, Luigi Gnudi, Charles A. Herzog, Adriana M. HungTazeen Hasan Jafar, Meg Jardine, Vivekanand Jha, Linong Ji, Steven E. Kahn, Robyn G. Langham, Edgar V. Lerma, Ronald C W Ma, Hirofumi Makino, Michel Marre, Michael Mauer, Kaj Metsärinne, Robert G. Nelson, Roberto Pecoits-Filho, Carol A. Pollock, Mohan Rajapurkar, Peter Rossing, Ivan Rychlík, Kumar Sharma, Robert C. Stanton, Vladimír Tesař, Ilkka Tikkanen, Charlie R V Tomson, Robert D. Toto, Yusuke Tsukamoto, Katherine R. Tuttle, Takashi Wada, Winfred W. Williams, Hong Zhang, Sophia Zoungas

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

The prevalence of diabetes around the world has reached epidemic proportions and is projected to increase to 642 million people by 2040. Diabetes is already the leading cause of end-stage kidney disease (ESKD) in most developed countries, and the growth in the number of people with ESKD around the world parallels the increase in diabetes. The presence of kidney disease is associated with a markedly elevated risk of cardiovascular disease and death in people with diabetes. Several new therapies and novel investigational agents targeting chronic kidney disease patients with diabetes are now under development. This conference was convened to assess our current state of knowledge regarding optimal glycemic control, current antidiabetic agents and their safety, and new therapies being developed to improve kidney function and cardiovascular outcomes for this vulnerable population.

Original languageEnglish (US)
Pages (from-to)1175-1183
Number of pages9
JournalKidney International
Volume90
Issue number6
DOIs
StatePublished - Dec 1 2016

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Kidney Diseases
Chronic Kidney Failure
Investigational Therapies
Vulnerable Populations
Chronic Renal Insufficiency
Developed Countries
Hypoglycemic Agents
Cardiovascular Diseases
Kidney
Safety
Growth
Therapeutics

Keywords

  • antidiabetic agents
  • cardiovascular disease
  • chronic kidney disease
  • diabetes
  • glycemic control
  • renoprotection

ASJC Scopus subject areas

  • Medicine(all)
  • Nephrology

Cite this

Management of patients with diabetes and CKD :  conclusions from a “Kidney Disease: Improving Global Outcomes” (KDIGO) Controversies Conference. / Perkovic, Vlado; Agarwal, Rajiv; Fioretto, Paola; Hemmelgarn, Brenda R.; Levin, Adeera; Thomas, Merlin C.; Wanner, Christoph; Kasiske, Bertram L.; Wheeler, David C.; Groop, Per Henrik; Bakris, George L.; Cooper, Mark E.; Chae, Dong Wan; Davidson, Michael H.; de Boer, Ian H.; de Zeeuw, Dick; Fornoni, Alessia; Gnudi, Luigi; Herzog, Charles A.; Hung, Adriana M.; Jafar, Tazeen Hasan; Jardine, Meg; Jha, Vivekanand; Ji, Linong; Kahn, Steven E.; Langham, Robyn G.; Lerma, Edgar V.; Ma, Ronald C W; Makino, Hirofumi; Marre, Michel; Mauer, Michael; Metsärinne, Kaj; Nelson, Robert G.; Pecoits-Filho, Roberto; Pollock, Carol A.; Rajapurkar, Mohan; Rossing, Peter; Rychlík, Ivan; Sharma, Kumar; Stanton, Robert C.; Tesař, Vladimír; Tikkanen, Ilkka; Tomson, Charlie R V; Toto, Robert D.; Tsukamoto, Yusuke; Tuttle, Katherine R.; Wada, Takashi; Williams, Winfred W.; Zhang, Hong; Zoungas, Sophia.

In: Kidney International, Vol. 90, No. 6, 01.12.2016, p. 1175-1183.

Research output: Contribution to journalArticle

Perkovic, V, Agarwal, R, Fioretto, P, Hemmelgarn, BR, Levin, A, Thomas, MC, Wanner, C, Kasiske, BL, Wheeler, DC, Groop, PH, Bakris, GL, Cooper, ME, Chae, DW, Davidson, MH, de Boer, IH, de Zeeuw, D, Fornoni, A, Gnudi, L, Herzog, CA, Hung, AM, Jafar, TH, Jardine, M, Jha, V, Ji, L, Kahn, SE, Langham, RG, Lerma, EV, Ma, RCW, Makino, H, Marre, M, Mauer, M, Metsärinne, K, Nelson, RG, Pecoits-Filho, R, Pollock, CA, Rajapurkar, M, Rossing, P, Rychlík, I, Sharma, K, Stanton, RC, Tesař, V, Tikkanen, I, Tomson, CRV, Toto, RD, Tsukamoto, Y, Tuttle, KR, Wada, T, Williams, WW, Zhang, H & Zoungas, S 2016, 'Management of patients with diabetes and CKD:  conclusions from a “Kidney Disease: Improving Global Outcomes” (KDIGO) Controversies Conference', Kidney International, vol. 90, no. 6, pp. 1175-1183. https://doi.org/10.1016/j.kint.2016.09.010
Perkovic, Vlado ; Agarwal, Rajiv ; Fioretto, Paola ; Hemmelgarn, Brenda R. ; Levin, Adeera ; Thomas, Merlin C. ; Wanner, Christoph ; Kasiske, Bertram L. ; Wheeler, David C. ; Groop, Per Henrik ; Bakris, George L. ; Cooper, Mark E. ; Chae, Dong Wan ; Davidson, Michael H. ; de Boer, Ian H. ; de Zeeuw, Dick ; Fornoni, Alessia ; Gnudi, Luigi ; Herzog, Charles A. ; Hung, Adriana M. ; Jafar, Tazeen Hasan ; Jardine, Meg ; Jha, Vivekanand ; Ji, Linong ; Kahn, Steven E. ; Langham, Robyn G. ; Lerma, Edgar V. ; Ma, Ronald C W ; Makino, Hirofumi ; Marre, Michel ; Mauer, Michael ; Metsärinne, Kaj ; Nelson, Robert G. ; Pecoits-Filho, Roberto ; Pollock, Carol A. ; Rajapurkar, Mohan ; Rossing, Peter ; Rychlík, Ivan ; Sharma, Kumar ; Stanton, Robert C. ; Tesař, Vladimír ; Tikkanen, Ilkka ; Tomson, Charlie R V ; Toto, Robert D. ; Tsukamoto, Yusuke ; Tuttle, Katherine R. ; Wada, Takashi ; Williams, Winfred W. ; Zhang, Hong ; Zoungas, Sophia. / Management of patients with diabetes and CKD :  conclusions from a “Kidney Disease: Improving Global Outcomes” (KDIGO) Controversies Conference. In: Kidney International. 2016 ; Vol. 90, No. 6. pp. 1175-1183.
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abstract = "The prevalence of diabetes around the world has reached epidemic proportions and is projected to increase to 642 million people by 2040. Diabetes is already the leading cause of end-stage kidney disease (ESKD) in most developed countries, and the growth in the number of people with ESKD around the world parallels the increase in diabetes. The presence of kidney disease is associated with a markedly elevated risk of cardiovascular disease and death in people with diabetes. Several new therapies and novel investigational agents targeting chronic kidney disease patients with diabetes are now under development. This conference was convened to assess our current state of knowledge regarding optimal glycemic control, current antidiabetic agents and their safety, and new therapies being developed to improve kidney function and cardiovascular outcomes for this vulnerable population.",
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