Measurement of panic-like responses following intravenous infusion of sodium lactate in panic-prone rats.

Tammy J. Sajdyk, Stanley R. Keim, Shelley R. Thielen, Stephanie D. Fitz, Anantha Shekhar

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

This unit describes a putative animal model for panic disorder. The basic premise is that pharmacological disruption of critical brain regions implicated in the circuitry of anxiety will lead to a condition similar to that of the human disorder. A clinically relevant test, the sodium lactate challenge, is utilized to assess parallels between the human condition and this rat model.

Original languageEnglish
JournalCurrent Protocols in Neuroscience
VolumeChapter 9
StatePublished - Nov 2003

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Sodium Lactate
Panic
Intravenous Infusions
Panic Disorder
Anxiety
Animal Models
Pharmacology
Brain

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Measurement of panic-like responses following intravenous infusion of sodium lactate in panic-prone rats. / Sajdyk, Tammy J.; Keim, Stanley R.; Thielen, Shelley R.; Fitz, Stephanie D.; Shekhar, Anantha.

In: Current Protocols in Neuroscience, Vol. Chapter 9, 11.2003.

Research output: Contribution to journalArticle

Sajdyk, Tammy J. ; Keim, Stanley R. ; Thielen, Shelley R. ; Fitz, Stephanie D. ; Shekhar, Anantha. / Measurement of panic-like responses following intravenous infusion of sodium lactate in panic-prone rats. In: Current Protocols in Neuroscience. 2003 ; Vol. Chapter 9.
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