Measurement of panic-like responses following intravenous infusion of sodium lactate in panic-prone rats.

Tammy J. Sajdyk, Stanley R. Keim, Shelley R. Thielen, Stephanie D. Fitz, Anantha Shekhar

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Abstract

This unit describes a putative animal model for panic disorder. The basic premise is that pharmacological disruption of critical brain regions implicated in the circuitry of anxiety will lead to a condition similar to that of the human disorder. A clinically relevant test, the sodium lactate challenge, is utilized to assess parallels between the human condition and this rat model.

Original languageEnglish (US)
Pages (from-to)Unit 9.17
JournalCurrent protocols in neuroscience / editorial board, Jacqueline N. Crawley ... [et al.]
VolumeChapter 9
StatePublished - Nov 2003

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ASJC Scopus subject areas

  • Neuroscience(all)

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