Mechanical and morphological effects of strain rate on fatigue of compact bone

M. B. Schaffler, E. L. Radin, D. B. Burr

Research output: Contribution to journalArticle

255 Scopus citations

Abstract

Compact bone specimens were cyclically loaded in uniaxial tension for one million cycles; loading was performed at either of two physiological strain rates (0.01 s-1 or 0.03 s-1) and a physiological strain range (0-1200 microstrain). Microdamage in loaded and nonloaded control specimens was then assessed histomorphometrically. Fatigue, evidence by stiffness loss, was observed at both strain rates and was significantly greater in specimens loaded at the high experimental strain rate than in specimens loaded at the low strain rate. Morphologically, this fatigue corresponded to increased numbers of microcracks in the bone. These data show that fatigue and resultant microdamage are realistic expectations of cyclic loading within the physiological strain range. The rate at which strains are developed influences the fatigue behavior of compact bone, suggesting that cyclic loading at high physiological strain rates, characteristic of vigorous activities, is more damaging to compact bone than loading at lower physiological strain rates.

Original languageEnglish (US)
Pages (from-to)207-214
Number of pages8
JournalBone
Volume10
Issue number3
DOIs
StatePublished - 1989

    Fingerprint

Keywords

  • Compact bone
  • Fatigue
  • Microdamage
  • Strain
  • Strain rate

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Physiology
  • Histology

Cite this