Mechanisms of atrial fibrillation and flutter and implications for management

Peng Sheng Chen, Charles A. Athill, Tsu Juey Wu, Takanori Ikeda, James J.C. Ong, Hrayr S. Karagueuzian

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

Both electrophysiologic and anatomical substrates are important in the generation and maintenance of atrial fibrillation. This review discusses the nature of re-entrant wavefronts in atrial fibrillation and the importance of anatomical structures, such as the pectinate muscles, in the generation and maintenance of re-entry. The involvement of the pectinate muscle structure on intra-atrial re-entry may have significant implications for both ablation and pharmacologic management of patients with atrial fibrillation. Copyright (C) 1999 Excerpta Medica Inc.

Original languageEnglish (US)
Pages (from-to)125-130
Number of pages6
JournalAmerican Journal of Cardiology
Volume84
Issue number9 SUPPL. 1
DOIs
StatePublished - Nov 4 1999

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ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Chen, P. S., Athill, C. A., Wu, T. J., Ikeda, T., Ong, J. J. C., & Karagueuzian, H. S. (1999). Mechanisms of atrial fibrillation and flutter and implications for management. American Journal of Cardiology, 84(9 SUPPL. 1), 125-130. https://doi.org/10.1016/S0002-9149(99)00712-2