Meningitis due to Ochrobactrum anthropi

An emerging nosocomial pathogen: A report of 3 cases

John Christenson, Andrew T. Pavia, Kay Seskin, Douglas Brockmeyer, E. Kent Korgenski, Eileen Jenkins, Jan Pierce, Judy A. Daly

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

We describe 3 cases of Ochrobactrum anthropi meningitis following the implantation of pericardial allograft tissue to cover dural defects following craniotomy. Following an extensive epidemiologic investigation, the tissue allograft was found to have been contaminated with this unusual organism during the harvesting and processing of the tissue in the tissue bank. This organism was only susceptible to imipenem, tetracycline, gentamicin, and ciprofloxacin. The clinical presentation of these patients was subacute. Two of the patients developed osteomyelitis of the bone flap; while another developed a relapse of infection along a former ventriculoperitoneal shunt track 6 months after the initial infection. Appropriate clinical outcome was only observed after removal of tissue allograft implants, debridement of devitalized tissue and bone, removal of shunt devices, and prolonged courses of antibiotics. No deaths were observed.

Original languageEnglish (US)
Pages (from-to)218-221
Number of pages4
JournalPediatric Neurosurgery
Volume27
Issue number4
StatePublished - 1997
Externally publishedYes

Fingerprint

Ochrobactrum anthropi
Meningitis
Allografts
Tissue and Organ Harvesting
Tissue Banks
Device Removal
Bone and Bones
Ventriculoperitoneal Shunt
Imipenem
Craniotomy
Debridement
Osteomyelitis
Ciprofloxacin
Infection
Gentamicins
Tetracycline
Anti-Bacterial Agents
Recurrence

Keywords

  • Meningitis
  • Ochrobactrum anthropi
  • Pericardial tissue allografts

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

Cite this

Christenson, J., Pavia, A. T., Seskin, K., Brockmeyer, D., Kent Korgenski, E., Jenkins, E., ... Daly, J. A. (1997). Meningitis due to Ochrobactrum anthropi: An emerging nosocomial pathogen: A report of 3 cases. Pediatric Neurosurgery, 27(4), 218-221.

Meningitis due to Ochrobactrum anthropi : An emerging nosocomial pathogen: A report of 3 cases. / Christenson, John; Pavia, Andrew T.; Seskin, Kay; Brockmeyer, Douglas; Kent Korgenski, E.; Jenkins, Eileen; Pierce, Jan; Daly, Judy A.

In: Pediatric Neurosurgery, Vol. 27, No. 4, 1997, p. 218-221.

Research output: Contribution to journalArticle

Christenson, J, Pavia, AT, Seskin, K, Brockmeyer, D, Kent Korgenski, E, Jenkins, E, Pierce, J & Daly, JA 1997, 'Meningitis due to Ochrobactrum anthropi: An emerging nosocomial pathogen: A report of 3 cases', Pediatric Neurosurgery, vol. 27, no. 4, pp. 218-221.
Christenson J, Pavia AT, Seskin K, Brockmeyer D, Kent Korgenski E, Jenkins E et al. Meningitis due to Ochrobactrum anthropi: An emerging nosocomial pathogen: A report of 3 cases. Pediatric Neurosurgery. 1997;27(4):218-221.
Christenson, John ; Pavia, Andrew T. ; Seskin, Kay ; Brockmeyer, Douglas ; Kent Korgenski, E. ; Jenkins, Eileen ; Pierce, Jan ; Daly, Judy A. / Meningitis due to Ochrobactrum anthropi : An emerging nosocomial pathogen: A report of 3 cases. In: Pediatric Neurosurgery. 1997 ; Vol. 27, No. 4. pp. 218-221.
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