Mesenteric vein thrombosis and vascular plasminogen activator

Orest Boyko, S. V. Pizzo

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

A 60-year-old woman with livedo reticularis was examined for defective release of vascular plasminogen activator by a newly described chromogenic assay. Her activator level was only 0.007 Committee on Thrombolytic Agents (CTA) units/mL, compared with a mean of 0.19 CTA units/mL for 84 female controls. Subsequently, the patient died as a result of thrombosis of the portal, splenic, hepatic and superior mesenteric veins with small-bowel infarction. The patient's family had a history of deep and superficial vein thrombosis. Her family's medical history was similar to a recently described pedigree, with low levels of releasable plasminogen activator associated with venous thrombosis. We believe that mesenteric vein thrombosis is a serious potential consequence of defective release of vascular plasminogen activator.

Original languageEnglish (US)
Pages (from-to)541-542
Number of pages2
JournalArchives of Pathology and Laboratory Medicine
Volume107
Issue number10
StatePublished - 1983
Externally publishedYes

Fingerprint

Mesenteric Veins
Plasminogen Activators
Blood Vessels
Thrombosis
Fibrinolytic Agents
Venous Thrombosis
Medical History Taking
Livedo Reticularis
Pedigree
Infarction
Liver

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology

Cite this

Mesenteric vein thrombosis and vascular plasminogen activator. / Boyko, Orest; Pizzo, S. V.

In: Archives of Pathology and Laboratory Medicine, Vol. 107, No. 10, 1983, p. 541-542.

Research output: Contribution to journalArticle

Boyko, Orest ; Pizzo, S. V. / Mesenteric vein thrombosis and vascular plasminogen activator. In: Archives of Pathology and Laboratory Medicine. 1983 ; Vol. 107, No. 10. pp. 541-542.
@article{18cabcce8e544f1a85b0de3a6da0e28e,
title = "Mesenteric vein thrombosis and vascular plasminogen activator",
abstract = "A 60-year-old woman with livedo reticularis was examined for defective release of vascular plasminogen activator by a newly described chromogenic assay. Her activator level was only 0.007 Committee on Thrombolytic Agents (CTA) units/mL, compared with a mean of 0.19 CTA units/mL for 84 female controls. Subsequently, the patient died as a result of thrombosis of the portal, splenic, hepatic and superior mesenteric veins with small-bowel infarction. The patient's family had a history of deep and superficial vein thrombosis. Her family's medical history was similar to a recently described pedigree, with low levels of releasable plasminogen activator associated with venous thrombosis. We believe that mesenteric vein thrombosis is a serious potential consequence of defective release of vascular plasminogen activator.",
author = "Orest Boyko and Pizzo, {S. V.}",
year = "1983",
language = "English (US)",
volume = "107",
pages = "541--542",
journal = "Archives of Pathology and Laboratory Medicine",
issn = "0003-9985",
publisher = "College of American Pathologists",
number = "10",

}

TY - JOUR

T1 - Mesenteric vein thrombosis and vascular plasminogen activator

AU - Boyko, Orest

AU - Pizzo, S. V.

PY - 1983

Y1 - 1983

N2 - A 60-year-old woman with livedo reticularis was examined for defective release of vascular plasminogen activator by a newly described chromogenic assay. Her activator level was only 0.007 Committee on Thrombolytic Agents (CTA) units/mL, compared with a mean of 0.19 CTA units/mL for 84 female controls. Subsequently, the patient died as a result of thrombosis of the portal, splenic, hepatic and superior mesenteric veins with small-bowel infarction. The patient's family had a history of deep and superficial vein thrombosis. Her family's medical history was similar to a recently described pedigree, with low levels of releasable plasminogen activator associated with venous thrombosis. We believe that mesenteric vein thrombosis is a serious potential consequence of defective release of vascular plasminogen activator.

AB - A 60-year-old woman with livedo reticularis was examined for defective release of vascular plasminogen activator by a newly described chromogenic assay. Her activator level was only 0.007 Committee on Thrombolytic Agents (CTA) units/mL, compared with a mean of 0.19 CTA units/mL for 84 female controls. Subsequently, the patient died as a result of thrombosis of the portal, splenic, hepatic and superior mesenteric veins with small-bowel infarction. The patient's family had a history of deep and superficial vein thrombosis. Her family's medical history was similar to a recently described pedigree, with low levels of releasable plasminogen activator associated with venous thrombosis. We believe that mesenteric vein thrombosis is a serious potential consequence of defective release of vascular plasminogen activator.

UR - http://www.scopus.com/inward/record.url?scp=0020518209&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0020518209&partnerID=8YFLogxK

M3 - Article

C2 - 6688517

AN - SCOPUS:0020518209

VL - 107

SP - 541

EP - 542

JO - Archives of Pathology and Laboratory Medicine

JF - Archives of Pathology and Laboratory Medicine

SN - 0003-9985

IS - 10

ER -