Metabolic diagnosis and medical prevention of calcium nephrolithiasis and its systemic manifestations: a consensus statement

The Consensus Conference Group, The Consensus Conference Group

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

Background: Recently published guidelines on the medical management of renal stone disease did not address relevant topics in the field of idiopathic calcium nephrolithiasis, which are important also for clinical research. Design: A steering committee identified 27 questions, which were proposed to a faculty of 44 experts in nephrolithiasis and allied fields. A systematic review of the literature was conducted and 5216 potentially relevant articles were selected; from these, 407 articles were deemed to provide useful scientific information. The Faculty, divided into working groups, analysed the relevant literature. Preliminary statements developed by each group were exhaustively discussed in plenary sessions and approved. Results: Statements were developed to inform clinicians on the identification of secondary forms of calcium nephrolithiasis and systemic complications; on the definition of idiopathic calcium nephrolithiasis; on the use of urinary tests of crystallization and of surgical observations during stone treatment in the management of these patients; on the identification of patients warranting preventive measures; on the role of fluid and nutritional measures and of drugs to prevent recurrent episodes of stones; and finally, on the cooperation between the urologist and nephrologist in the renal stone patients. Conclusions: This document has addressed idiopathic calcium nephrolithiasis from the perspective of a disease that can associate with systemic disorders, emphasizing the interplay needed between urologists and nephrologists. It is complementary to the American Urological Association and European Association of Urology guidelines. Future areas for research are identified.

Original languageEnglish (US)
Pages (from-to)715-734
Number of pages20
JournalJournal of Nephrology
Volume29
Issue number6
DOIs
StatePublished - Dec 1 2016

Fingerprint

Nephrolithiasis
Calcium
Guidelines
Kidney
Crystallization
Research
Pharmaceutical Preparations

Keywords

  • Beverages
  • Bone disease
  • CKD
  • Diet
  • Nephrolithiasis
  • Renal tubular acidosis

ASJC Scopus subject areas

  • Nephrology

Cite this

Metabolic diagnosis and medical prevention of calcium nephrolithiasis and its systemic manifestations : a consensus statement. / The Consensus Conference Group; The Consensus Conference Group.

In: Journal of Nephrology, Vol. 29, No. 6, 01.12.2016, p. 715-734.

Research output: Contribution to journalArticle

The Consensus Conference Group ; The Consensus Conference Group. / Metabolic diagnosis and medical prevention of calcium nephrolithiasis and its systemic manifestations : a consensus statement. In: Journal of Nephrology. 2016 ; Vol. 29, No. 6. pp. 715-734.
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abstract = "Background: Recently published guidelines on the medical management of renal stone disease did not address relevant topics in the field of idiopathic calcium nephrolithiasis, which are important also for clinical research. Design: A steering committee identified 27 questions, which were proposed to a faculty of 44 experts in nephrolithiasis and allied fields. A systematic review of the literature was conducted and 5216 potentially relevant articles were selected; from these, 407 articles were deemed to provide useful scientific information. The Faculty, divided into working groups, analysed the relevant literature. Preliminary statements developed by each group were exhaustively discussed in plenary sessions and approved. Results: Statements were developed to inform clinicians on the identification of secondary forms of calcium nephrolithiasis and systemic complications; on the definition of idiopathic calcium nephrolithiasis; on the use of urinary tests of crystallization and of surgical observations during stone treatment in the management of these patients; on the identification of patients warranting preventive measures; on the role of fluid and nutritional measures and of drugs to prevent recurrent episodes of stones; and finally, on the cooperation between the urologist and nephrologist in the renal stone patients. Conclusions: This document has addressed idiopathic calcium nephrolithiasis from the perspective of a disease that can associate with systemic disorders, emphasizing the interplay needed between urologists and nephrologists. It is complementary to the American Urological Association and European Association of Urology guidelines. Future areas for research are identified.",
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T1 - Metabolic diagnosis and medical prevention of calcium nephrolithiasis and its systemic manifestations

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AU - Croppi, Emanuele

AU - Coe, Fredric

AU - Lingeman, James

AU - Moe, Orson

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AU - Curhan, Gary C.

AU - Ferraro, Pietro Manuel

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AU - Goldfarb, David S.

AU - Heilberg, Ita Pfeferman

AU - Hess, Bernard

AU - Lieske, John

AU - Marangella, Martino

AU - Milliner, Dawn

AU - Preminger, Glen M.

AU - Reis Santos, Jose’ Manuel

AU - Sakhaee, Khashayar

AU - Sarica, Kemal

AU - Siener, Roswitha

AU - Strazzullo, Pasquale

AU - Williams, James

AU - Bartoletti, R.

AU - Buchholz, N.

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AU - Capasso, G. B.

AU - Cicerello, E.

AU - Coe, F.

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AU - Goldfarb, D. S.

AU - Heilberg, I. P.

AU - Hess, B.

AU - Jaeger, Ph

AU - Kirkali, Z.

AU - Kok, D.

AU - Letavernier, E.

AU - Lieske, J.

AU - Lingeman, J.

AU - Marangella, M.

AU - Mazzaferro, S.

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AU - Milliner, D.

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KW - Beverages

KW - Bone disease

KW - CKD

KW - Diet

KW - Nephrolithiasis

KW - Renal tubular acidosis

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