Metanephric adenoma vs. Wilms' tumor: A report of 2 cases with diagnosis by fine needle aspiration and cytologic comparisons

Said Khayyata, David Grignon, Michael R. Aulicino, Mousa A. Al-Abbadi

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Background: Metanephric adenoma (MA) is a rare benign renal neoplasm that can occur at any age, whereas, Wilms' tumor (WT) is the most common malignant renal neoplasm in children and is occasionally seen in adults. Cases: In case 1, a 26-year-old male had a left renal mass. Fine needle aspiration (FNA) showed 3-dimensional sheets of cells with nuclear overlapping, molding, irregular nuclear membrane and distinct nucleoli. Frequent mitotic figures could be seen. The cytologic differential diagnosis included Wilms' tumor, neuroectodermal tumor and metanephric adenoma. Nephrectomy revealed Wilms' tumor. In case 2, a 24-year-old female presented with erythrocytosis and a right renal mass. FNA showed small, uniform cells with smooth nuclear membrane, fine chromatin and inconspicuous nucleoli. A diagnosis of metanephric adenoma was made and confirmed on nephrectomy. Conclusion: Differentiating MA from WT based on cytologic features on FNA biopsy prior to surgical resection can be difficult.

Original languageEnglish (US)
Pages (from-to)464-467
Number of pages4
JournalActa Cytologica
Volume51
Issue number3
StatePublished - 2007
Externally publishedYes

Fingerprint

Wilms Tumor
Fine Needle Biopsy
Adenoma
Kidney Neoplasms
Nuclear Envelope
Nephrectomy
Neuroectodermal Tumors
Kidney
Polycythemia
Chromatin
Differential Diagnosis
Neoplasms

Keywords

  • Adenoma
  • Aspiration biopsy, fine-needle
  • Kidney neoplasms
  • Metanephric adenoma
  • Wilms' tumor

ASJC Scopus subject areas

  • Anatomy
  • Cell Biology
  • Histology

Cite this

Metanephric adenoma vs. Wilms' tumor : A report of 2 cases with diagnosis by fine needle aspiration and cytologic comparisons. / Khayyata, Said; Grignon, David; Aulicino, Michael R.; Al-Abbadi, Mousa A.

In: Acta Cytologica, Vol. 51, No. 3, 2007, p. 464-467.

Research output: Contribution to journalArticle

Khayyata, Said ; Grignon, David ; Aulicino, Michael R. ; Al-Abbadi, Mousa A. / Metanephric adenoma vs. Wilms' tumor : A report of 2 cases with diagnosis by fine needle aspiration and cytologic comparisons. In: Acta Cytologica. 2007 ; Vol. 51, No. 3. pp. 464-467.
@article{8dd83ebab7fe4fe6913b334455833031,
title = "Metanephric adenoma vs. Wilms' tumor: A report of 2 cases with diagnosis by fine needle aspiration and cytologic comparisons",
abstract = "Background: Metanephric adenoma (MA) is a rare benign renal neoplasm that can occur at any age, whereas, Wilms' tumor (WT) is the most common malignant renal neoplasm in children and is occasionally seen in adults. Cases: In case 1, a 26-year-old male had a left renal mass. Fine needle aspiration (FNA) showed 3-dimensional sheets of cells with nuclear overlapping, molding, irregular nuclear membrane and distinct nucleoli. Frequent mitotic figures could be seen. The cytologic differential diagnosis included Wilms' tumor, neuroectodermal tumor and metanephric adenoma. Nephrectomy revealed Wilms' tumor. In case 2, a 24-year-old female presented with erythrocytosis and a right renal mass. FNA showed small, uniform cells with smooth nuclear membrane, fine chromatin and inconspicuous nucleoli. A diagnosis of metanephric adenoma was made and confirmed on nephrectomy. Conclusion: Differentiating MA from WT based on cytologic features on FNA biopsy prior to surgical resection can be difficult.",
keywords = "Adenoma, Aspiration biopsy, fine-needle, Kidney neoplasms, Metanephric adenoma, Wilms' tumor",
author = "Said Khayyata and David Grignon and Aulicino, {Michael R.} and Al-Abbadi, {Mousa A.}",
year = "2007",
language = "English (US)",
volume = "51",
pages = "464--467",
journal = "Acta Cytologica",
issn = "0001-5547",
publisher = "Science Printers and Publishers Inc.",
number = "3",

}

TY - JOUR

T1 - Metanephric adenoma vs. Wilms' tumor

T2 - A report of 2 cases with diagnosis by fine needle aspiration and cytologic comparisons

AU - Khayyata, Said

AU - Grignon, David

AU - Aulicino, Michael R.

AU - Al-Abbadi, Mousa A.

PY - 2007

Y1 - 2007

N2 - Background: Metanephric adenoma (MA) is a rare benign renal neoplasm that can occur at any age, whereas, Wilms' tumor (WT) is the most common malignant renal neoplasm in children and is occasionally seen in adults. Cases: In case 1, a 26-year-old male had a left renal mass. Fine needle aspiration (FNA) showed 3-dimensional sheets of cells with nuclear overlapping, molding, irregular nuclear membrane and distinct nucleoli. Frequent mitotic figures could be seen. The cytologic differential diagnosis included Wilms' tumor, neuroectodermal tumor and metanephric adenoma. Nephrectomy revealed Wilms' tumor. In case 2, a 24-year-old female presented with erythrocytosis and a right renal mass. FNA showed small, uniform cells with smooth nuclear membrane, fine chromatin and inconspicuous nucleoli. A diagnosis of metanephric adenoma was made and confirmed on nephrectomy. Conclusion: Differentiating MA from WT based on cytologic features on FNA biopsy prior to surgical resection can be difficult.

AB - Background: Metanephric adenoma (MA) is a rare benign renal neoplasm that can occur at any age, whereas, Wilms' tumor (WT) is the most common malignant renal neoplasm in children and is occasionally seen in adults. Cases: In case 1, a 26-year-old male had a left renal mass. Fine needle aspiration (FNA) showed 3-dimensional sheets of cells with nuclear overlapping, molding, irregular nuclear membrane and distinct nucleoli. Frequent mitotic figures could be seen. The cytologic differential diagnosis included Wilms' tumor, neuroectodermal tumor and metanephric adenoma. Nephrectomy revealed Wilms' tumor. In case 2, a 24-year-old female presented with erythrocytosis and a right renal mass. FNA showed small, uniform cells with smooth nuclear membrane, fine chromatin and inconspicuous nucleoli. A diagnosis of metanephric adenoma was made and confirmed on nephrectomy. Conclusion: Differentiating MA from WT based on cytologic features on FNA biopsy prior to surgical resection can be difficult.

KW - Adenoma

KW - Aspiration biopsy, fine-needle

KW - Kidney neoplasms

KW - Metanephric adenoma

KW - Wilms' tumor

UR - http://www.scopus.com/inward/record.url?scp=34248655438&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34248655438&partnerID=8YFLogxK

M3 - Article

C2 - 17536557

AN - SCOPUS:34248655438

VL - 51

SP - 464

EP - 467

JO - Acta Cytologica

JF - Acta Cytologica

SN - 0001-5547

IS - 3

ER -