Metastatic pancreatic endocrine tumor presenting as thoracic spinal cord compression

Todd Alin Eads, Eyas M. Hattab, Richard Rodgers

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

STUDY DESIGN.: A case report. OBJECTIVE.: The authors present a rare case of metastatic nonfunctioning neuroendocrine tumor of the pancreas presenting as thoracic spinal cord compression. SUMMARY OF BACKGROUND DATA.: Pancreatic endocrine tumors (PETs) are a slow-growing subset of pancreatic tumors. They can be classified as either functioning or nonfunctioning. To our knowledge, this is the second reported case of a PET presenting as spinal cord compression. METHODS.: The clinical course, radiologic features, pathology, and outcome of the metastasis of PET are reported. RESULTS.: A 59-year-old woman presenting with a 2-week history of midthoracic back pain and early signs of myelopathy. A computed tomography scan and magnetic resonance imaging revealed multiple mildly enhancing lesions within T5, T7, T8, and L1 vertebral bodies with ventral epidural and bilateral T8-T9 neuroforaminal soft tissue extension causing severe spinal canal stenosis. A computed tomography-guided biopsy was inconclusive, and we performed a T7-T9 laminectomy with T8 bilateral transpedicular decompression and T6 to T10 pedicle screw fixation and posterolateral fusion with subtotal resection of the tumor. Pathology was consistent with low-grade neuroendocrine tumor. The patient recovered well, and an octreotide scan ultimately revealed an area of abnormal uptake within the body of the pancreas. CONCLUSION.: We have reported a rare case of a metastatic PET presenting as spinal cord compression.

Original languageEnglish
JournalSpine
Volume35
Issue number11
DOIs
StatePublished - May 15 2010

Fingerprint

Spinal Cord Compression
Thorax
Neoplasms
Neuroendocrine Tumors
Pancreas
Tomography
Pathology
Spinal Stenosis
Spinal Canal
Laminectomy
Octreotide
Spinal Cord Diseases
Back Pain
Decompression
Magnetic Resonance Imaging
Neoplasm Metastasis
Biopsy

Keywords

  • Metastasis
  • Neuroendocrine tumor
  • Pancreatic tumor
  • Spinal cord compression
  • Spine

ASJC Scopus subject areas

  • Clinical Neurology
  • Orthopedics and Sports Medicine

Cite this

Metastatic pancreatic endocrine tumor presenting as thoracic spinal cord compression. / Eads, Todd Alin; Hattab, Eyas M.; Rodgers, Richard.

In: Spine, Vol. 35, No. 11, 15.05.2010.

Research output: Contribution to journalArticle

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AB - STUDY DESIGN.: A case report. OBJECTIVE.: The authors present a rare case of metastatic nonfunctioning neuroendocrine tumor of the pancreas presenting as thoracic spinal cord compression. SUMMARY OF BACKGROUND DATA.: Pancreatic endocrine tumors (PETs) are a slow-growing subset of pancreatic tumors. They can be classified as either functioning or nonfunctioning. To our knowledge, this is the second reported case of a PET presenting as spinal cord compression. METHODS.: The clinical course, radiologic features, pathology, and outcome of the metastasis of PET are reported. RESULTS.: A 59-year-old woman presenting with a 2-week history of midthoracic back pain and early signs of myelopathy. A computed tomography scan and magnetic resonance imaging revealed multiple mildly enhancing lesions within T5, T7, T8, and L1 vertebral bodies with ventral epidural and bilateral T8-T9 neuroforaminal soft tissue extension causing severe spinal canal stenosis. A computed tomography-guided biopsy was inconclusive, and we performed a T7-T9 laminectomy with T8 bilateral transpedicular decompression and T6 to T10 pedicle screw fixation and posterolateral fusion with subtotal resection of the tumor. Pathology was consistent with low-grade neuroendocrine tumor. The patient recovered well, and an octreotide scan ultimately revealed an area of abnormal uptake within the body of the pancreas. CONCLUSION.: We have reported a rare case of a metastatic PET presenting as spinal cord compression.

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