Metastatic pancreatic endocrine tumor presenting as thoracic spinal cord compression

Todd Alin Eads, Eyas M. Hattab, Richard B. Rodgers

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

STUDY DESIGN.: A case report. OBJECTIVE.: The authors present a rare case of metastatic nonfunctioning neuroendocrine tumor of the pancreas presenting as thoracic spinal cord compression. SUMMARY OF BACKGROUND DATA.: Pancreatic endocrine tumors (PETs) are a slow-growing subset of pancreatic tumors. They can be classified as either functioning or nonfunctioning. To our knowledge, this is the second reported case of a PET presenting as spinal cord compression. METHODS.: The clinical course, radiologic features, pathology, and outcome of the metastasis of PET are reported. RESULTS.: A 59-year-old woman presenting with a 2-week history of midthoracic back pain and early signs of myelopathy. A computed tomography scan and magnetic resonance imaging revealed multiple mildly enhancing lesions within T5, T7, T8, and L1 vertebral bodies with ventral epidural and bilateral T8-T9 neuroforaminal soft tissue extension causing severe spinal canal stenosis. A computed tomography-guided biopsy was inconclusive, and we performed a T7-T9 laminectomy with T8 bilateral transpedicular decompression and T6 to T10 pedicle screw fixation and posterolateral fusion with subtotal resection of the tumor. Pathology was consistent with low-grade neuroendocrine tumor. The patient recovered well, and an octreotide scan ultimately revealed an area of abnormal uptake within the body of the pancreas. CONCLUSION.: We have reported a rare case of a metastatic PET presenting as spinal cord compression.

Original languageEnglish (US)
Pages (from-to)E510-E513
JournalSpine
Volume35
Issue number11
DOIs
StatePublished - May 15 2010

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Keywords

  • Metastasis
  • Neuroendocrine tumor
  • Pancreatic tumor
  • Spinal cord compression
  • Spine

ASJC Scopus subject areas

  • Clinical Neurology
  • Orthopedics and Sports Medicine

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