Metastatic vertebral disease in children

A. A. Freiberg, G. P. Graziano, Randall Loder, R. N. Hensinger

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We retrospectively reviewed 19 children with osseous vertebral metastases; The average age was 10.9 years at diagnosis of the primary tumor and 11.2 years at diagnosis of metastasis. The location of the multiple metastases was cervical (three), thoracic (14), and lumbar (10). Treatment consisted of chemotherapy (19), radiation therapy (12), and operation (seven). Ten children died at an average of 13 months after diagnosis of the primary tumor; nine are alive at an average of 72 months after diagnosis. All four children treated with chemotherapy spinal radiation, and laminectomy, and who survived >2 months, developed deformity. In this particular situation, we encourage consideration of spinal stabilization when it is appropriately coordinated with radiation and chemotherapy.

Original languageEnglish (US)
Pages (from-to)148-153
Number of pages6
JournalJournal of Pediatric Orthopaedics
Volume13
Issue number2
StatePublished - 1993
Externally publishedYes

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Neoplasm Metastasis
Drug Therapy
Radiation
Laminectomy
Neoplasms
Radiotherapy
Thorax
Therapeutics

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Pediatrics, Perinatology, and Child Health
  • Surgery

Cite this

Freiberg, A. A., Graziano, G. P., Loder, R., & Hensinger, R. N. (1993). Metastatic vertebral disease in children. Journal of Pediatric Orthopaedics, 13(2), 148-153.

Metastatic vertebral disease in children. / Freiberg, A. A.; Graziano, G. P.; Loder, Randall; Hensinger, R. N.

In: Journal of Pediatric Orthopaedics, Vol. 13, No. 2, 1993, p. 148-153.

Research output: Contribution to journalArticle

Freiberg, AA, Graziano, GP, Loder, R & Hensinger, RN 1993, 'Metastatic vertebral disease in children', Journal of Pediatric Orthopaedics, vol. 13, no. 2, pp. 148-153.
Freiberg AA, Graziano GP, Loder R, Hensinger RN. Metastatic vertebral disease in children. Journal of Pediatric Orthopaedics. 1993;13(2):148-153.
Freiberg, A. A. ; Graziano, G. P. ; Loder, Randall ; Hensinger, R. N. / Metastatic vertebral disease in children. In: Journal of Pediatric Orthopaedics. 1993 ; Vol. 13, No. 2. pp. 148-153.
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