Metastatic vertebral disease in children

A. A. Freiberg, G. P. Graziano, R. T. Loder, R. N. Hensinger

Research output: Contribution to journalArticle

1 Scopus citations


We retrospectively reviewed 19 children with osseous vertebral metastases; The average age was 10.9 years at diagnosis of the primary tumor and 11.2 years at diagnosis of metastasis. The location of the multiple metastases was cervical (three), thoracic (14), and lumbar (10). Treatment consisted of chemotherapy (19), radiation therapy (12), and operation (seven). Ten children died at an average of 13 months after diagnosis of the primary tumor; nine are alive at an average of 72 months after diagnosis. All four children treated with chemotherapy spinal radiation, and laminectomy, and who survived >2 months, developed deformity. In this particular situation, we encourage consideration of spinal stabilization when it is appropriately coordinated with radiation and chemotherapy.

Original languageEnglish (US)
Pages (from-to)148-153
Number of pages6
JournalJournal of Pediatric Orthopaedics
Issue number2
StatePublished - Jan 1 1993
Externally publishedYes

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Orthopedics and Sports Medicine

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    Freiberg, A. A., Graziano, G. P., Loder, R. T., & Hensinger, R. N. (1993). Metastatic vertebral disease in children. Journal of Pediatric Orthopaedics, 13(2), 148-153.